Evidence map›Paper›PMID 26661652›Full record

ArticleAmerican journal of physiology. Renal physiology2016

ROMK inhibitor actions in the nephron probed with diuretics.

Sujay V Kharade, Daniel Flores, Craig W Lindsley, Lisa M Satlin, Jerod S Denton

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sujay V KharadeDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Daniel FloresDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Craig W LindsleyDepartment of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.
Lisa M SatlinDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Jerod S DentonDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; Jerod.S.Denton@Vanderbilt.edu.
Vanderbilt University Medical Center · USIcahn School of Medicine at Mount Sinai · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
NIDDK NIH HHS P30 DK079307
6 · The paper itself

Abstract

Diuretics acting on specific nephron segments to inhibit Na

Indexed as

AmilorideAnimalsBenzimidazolesBumetanideDiuresisDiureticsDrug InteractionsHydrochlorothiazideNephronsPotassiumPotassium Channels, Inwardly RectifyingRatsSodium6-nitro-2-((6-nitro-1H-benzimidazol-2-yl)methoxymethyl)-1H-benzimidazoleAmiloridebenzamilBenzimidazolesBumetanideDiureticsHydrochlorothiazideKcnj1 protein, ratPotassiumPotassium Channels, Inwardly RectifyingSodiumhypertensionmechanismpharmacologypotassium, sodium

Identifiers

PMID26661652
PMCPMC4835929
OpenAlexW2208533417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.