Evidence map›Paper›PMID 26661526›Full record

ReviewPhysiology (Bethesda, Md.)2016

Novel Functions of Renin Precursors in Homeostasis and Disease.

R Ariel Gomez, Maria Luisa S Sequeira-Lopez

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Renin Cells, the Kidney, and Hypertension.Circulation research · 2021
    Review
  6. Phylogeny and ontogeny of the renin-angiotensin system: Current view and perspectives.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2021
    Review
  7. Ontogeny of renin gene expression in the chicken, Gallus gallus.General and comparative endocrinology · 2020
    Article
  8. Article
  9. Development of the renal vasculature.Seminars in cell & developmental biology · 2019
    Review
  10. Review
  11. Leukemia development initiated by deletion ofDisease models & mechanisms · 2018
    Article
  12. Review
  13. Article
  14. Review
  15. Interference with GsJournal of the American Society of Nephrology : JASN · 2017
    Article
  16. Juxtaglomerular Cell Phenotypic Plasticity.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Review
  17. Chronic Stimulation of Renin Cells Leads to Vascular Pathology.Hypertension (Dallas, Tex. : 1979) · 2017
    Article
  18. Fate of Renin Cells During Development and Disease.Hypertension (Dallas, Tex. : 1979) · 2017
    Review
  19. Plasticity of Renin Cells in the Kidney Vasculature.Current hypertension reports · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

R Ariel GomezUniversity of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia rg@virginia.edu msl7u@virginia.edu.
Maria Luisa S Sequeira-LopezUniversity of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia rg@virginia.edu msl7u@virginia.edu.
University of Virginia · US

Funding

Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI PATRICIO E. RAY · 2012 to 2026
$13.8M
Renin Cell Fate in the Kidney VasculatureR37HL066242 · NHLBI · UNIVERSITY OF VIRGINIA · PI GOMEZ, ROBERTO ARIEL · 2007 to 2016
$4.0M
Development of the Renal ArteriolesR01DK091330 · NIDDK · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2011 to 2015
$1.7M
Role of micro RNAs in renin cell differentiationR01HL096735 · NHLBI · UNIVERSITY OF VIRGINIA · PI GOMEZ, ROBERTO ARIEL · 2010 to 2013
$1.5M
NHLBI NIH HHS HL-096735NHLBI NIH HHS R01 HL096735NHLBI NIH HHS R37 HL066242NIDDK NIH HHS DK-091330NIDDK NIH HHS DK-096373NIDDK NIH HHS P50 DK096373NIDDK NIH HHS R01 DK091330
6 · The paper itself

Abstract

Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.

Indexed as

AnimalsBlood PressureBone MarrowHematopoiesisHomeostasisHumansNeoplasmsReninRenin-Angiotensin SystemRenin

Identifiers

PMID26661526
PMCPMC4698453
OpenAlexW2219996477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.