Evidence map›Paper›PMID 26661247›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2016

Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings.

Florian Schmid, Lydia Wachsmuth, Miriam Schwalm, Pierre-Hugues Prouvot, Eduardo Rosales Jubal, Consuelo Fois, Gautam Pramanik, Claus Zimmer, Cornelius Faber, Albrecht Stroh

Open access · hybridAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing.International journal of molecular sciences · 2022
    Pooled it
  2. Article
  3. Article
  4. High Spatiotemporal Resolution Radial Encoding Single-Vessel fMRI.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Hemodynamic transient and functional connectivity follow structural connectivity and cell type over the brain hierarchy.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  11. Review
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  19. Article
  20. Multimode Optical Fibers for Optical Neural Interfaces.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Florian SchmidDepartment of Clinical Radiology, University Hospital Münster, Münster, Germany.
Lydia WachsmuthDepartment of Clinical Radiology, University Hospital Münster, Münster, Germany.
Miriam SchwalmFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
Pierre-Hugues ProuvotFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
Eduardo Rosales JubalFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
Consuelo FoisFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
Gautam PramanikFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
Claus ZimmerDepartment of Neuroradiology, Technical University Munich, Munich, Germany.
Cornelius FaberDepartment of Clinical Radiology, University Hospital Münster, Münster, Germany faberc@uni-muenster.de.
Albrecht StrohFocus Program translational Neuroscience & Institute for Microscopic Anatomy and Neurobiology, Johannes Gutenberg-University Mainz, Mainz, Germany.
University Hospital Münster · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DEJohannes Gutenberg University Mainz · DEDiego Portales University · CLTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encoding of sensory inputs in the cortex is characterized by sparse neuronal network activation. Optogenetic stimulation has previously been combined with fMRI (ofMRI) to probe functional networks. However, for a quantitative optogenetic probing of sensory-driven sparse network activation, the level of similarity between sensory and optogenetic network activation needs to be explored. Here, we complement ofMRI with optic fiber-based population Ca

Indexed as

Aniline CompoundsAnimalsCalciumChannelrhodopsinsEvoked PotentialsFemaleFluoresceinsGenetic VectorsMagnetic Resonance ImagingMicroscopy, FluorescenceNeuronsOptical FibersOptogeneticsOxygenPhotic StimulationRats, Inbred F344Aniline CompoundsCalciumChannelrhodopsinsFluoresceinsOregon green 488 BAPTA-1Oxygencalcium recordingslight propagationoptical neurophysiologyOptogenetic fMRIsparse network activation

Identifiers

PMID26661247
PMCPMC5094300
OpenAlexW2282633626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.