ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2016
Relations between location and type of intracranial atherosclerosis and parenchymal damage.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL.Annals of clinical and translational neurology · 2025Article
- 7T MRI for Intracranial Vessel Wall Lesions and Its Associated Neurological Disorders: A Systematic Review.Brain sciences · 2022Review
- Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease: The SMART-MR study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Intracranial Atherosclerotic Burden and Cerebral Parenchymal Changes at 7T MRI in Patients With Transient Ischemic Attack or Ischemic Stroke.Frontiers in neurology · 2021Article
- Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Clinical vascular imaging in the brain at 7T.NeuroImage · 2018Review
- Detection, risk factors, and functional consequences of cerebral microinfarcts.The Lancet. Neurology · 2017Review
- High-resolution intracranial vessel wall MRI in an elderly asymptomatic population: comparison of 3T and 7T.European radiology · 2017Article
- Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study.Brain : a journal of neurology · 2016Article
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Authors and funding
9 authors.
Funding
Abstract
The aim of this study was to assess the relation between location and type of intracranial atherosclerosis (ICAS) and cortical microinfarcts (CMIs) and macroinfarcts in 18 patients presenting with ischemic stroke (n = 12) or transient ischemic attack (TIA) (n = 6) using 7 tesla MR imaging. The protocol included: 3D T2-weighted FLAIR and 3D T1-weighted Magnetization-Preparation Inversion Recovery Turbo Spin Echo sequence. ICAS lesions and infarcts were scored by two raters. The relation between ICAS lesions, calculated ratios of ICAS lesion characteristics, location, and infarcts were examined using linear regression analyses. A total number of 75 ICAS lesions (all patients), 101 CMIs (78% of patients), and 31 macroinfarcts (67% of patients) were found. Seventy-six and sixty-five percent of the CMIs and macroinfarcts, respectively, were found in the same vascular territory as the ICAS lesions (p = 0.977, p = 0.167, respectively). A positive correlation existed between the number of macroinfarcts and CMIs (p < 0.05). In patients with macroinfarcts, we found more concentric (p < 0.01) and diffuse (p < 0.05) type of ICAS lesions. A high prevalence of brain tissue lesions, both macroinfarcts and CMIs, were found in patients with ICAS. Macroinfarcts were found to be related to specific ICAS lesion types. The type of ICAS lesion seems to be promising as a marker for ICAS patients at higher risk of future infarcts.
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