ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2016
Quantifying fluctuations of resting state networks using arterial spin labeling perfusion MRI.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 55 citations in OpenAlex.
- Global fluctuations of cerebral blood flow indicate a global brain network independent of systemic factors.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Trial
- Aging, brain network connectivity, and cognition: evidence from resting-state dynamic arterial spin labeling.NeuroImage · 2026Article
- Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness.Communications biology · 2025Article
- Abnormal Cerebral Perfusion and Functional Connectivity in Women with Overactive Bladder.Brain sciences · 2025Article
- Age and gender-related patterns of arterial transit time and cerebral blood flow in healthy adults.NeuroImage · 2025Article
- Temporal Lobe Epilepsy Perturbs the Brain-Wide Excitation-Inhibition Balance: Associations with Microcircuit Organization, Clinical Parameters, and Cognitive Dysfunction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications.Magnetic resonance in medicine · 2024Review
- Pharmacological manipulation of neurotransmitter activity induces disparate effects on cerebral blood flow and resting-state fluctuations.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Effect of Meditation on Brain Activity during an Attention Task: A Comparison Study of ASL and BOLD Task fMRI.Brain sciences · 2023Article
- Global Functional Connectivity at Rest Is Associated with Attention: An Arterial Spin Labeling Study.Brain sciences · 2023Article
- Recent Technical Developments in ASL: A Review of the State of the Art.Magnetic resonance in medicine · 2022Review
- Arterial Spin Labeling Perfusion in Pediatric Brain Tumors: A Review of Techniques, Quality Control, and Quantification.Cancers · 2022Review
- The Longitudinal Effect of Meditation on Resting-State Functional Connectivity Using Dynamic Arterial Spin Labeling: A Feasibility Study.Brain sciences · 2021Article
- Mapping the orbitofrontal cortex using temporal fluctuations in cerebral blood flow.Brain and behavior · 2021Article
- The Role of the Thalamus in the Neurological Mechanism of Subjective Sleepiness: An fMRI Study.Nature and science of sleep · 2021Article
- Neural plasticity secondary to carpal tunnel syndrome: a pseudo-continuous arterial spin labeling study.Neural regeneration research · 2021Article
- Rotated spiral RARE for high spatial and temporal resolution volumetric arterial spin labeling acquisition.NeuroImage · 2020Article
- Consistent Cerebral Blood Flow Covariance Networks across Healthy Individuals and Their Similarity with Resting State Networks and Vascular Territories.Diagnostics (Basel, Switzerland) · 2020Article
- Personode: A Toolbox for ICA Map Classification and Individualized ROI Definition.Neuroinformatics · 2020Article
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4 authors at 1 institution in 1 country.
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Abstract
Blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has been widely used to investigate spontaneous low-frequency signal fluctuations across brain resting state networks. However, BOLD only provides relative measures of signal fluctuations. Arterial Spin Labeling (ASL) MRI holds great potential for quantitative measurements of resting state network fluctuations. This study systematically quantified signal fluctuations of the large-scale resting state networks using ASL data from 20 healthy volunteers by separating them from global signal fluctuations and fluctuations caused by residual noise. Global ASL signal fluctuation was 7.59% ± 1.47% relative to the ASL baseline perfusion. Fluctuations of seven detected resting state networks vary from 2.96% ± 0.93% to 6.71% ± 2.35%. Fluctuations of networks and residual noise were 6.05% ± 1.18% and 6.78% ± 1.16% using 4-mm resolution ASL data applied with Gaussian smoothing kernel of 6mm. However, network fluctuations were reduced by 7.77% ± 1.56% while residual noise fluctuation was markedly reduced by 39.75% ± 2.90% when smoothing kernel of 12 mm was applied to the ASL data. Therefore, global and network fluctuations are the dominant structured noise sources in ASL data. Quantitative measurements of resting state networks may enable improved noise reduction and provide insights into the function of healthy and diseased brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.