Evidence map›Paper›PMID 26661080›Full record

ArticleDer Anaesthesist2016

Impact of unsuspected subsegmental pulmonary embolism in ICU patients.

C Koch, R Schramm, F C Roller, A Hecker, M Henrich, E Schneck, G Krombach, M A Weigand, C Lichtenstern

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Article in Der Anaesthesist, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C KochDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany. christian.koch@chiru.med.uni-giessen.de.
R SchrammDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany.
F C RollerDepartment of Radiology, University Hospital of Giessen and Marburg, 35392, Giessen, Germany.
A HeckerDepartment of General, Visceral, Thoracic and Transplant Surgery, University Hospital of Giessen and Marburg, 35392, Giessen, Germany.
M HenrichDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany.
E SchneckDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany.
G KrombachDepartment of Radiology, University Hospital of Giessen and Marburg, 35392, Giessen, Germany.
M A WeigandDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany.
C LichtensternDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital of Giessen and Marburg, Rudolf-Buchheim-Street 7, 35392, Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritically ill patients in intensive-care units are at high risk for pulmonary embolism (PE). As a result of modern multi-detector computed tomographic angiography (MDCT) increased visualization of peripheral pulmonary arteries, isolated subsegmental pulmonary embolisms (ISSPE) are increasingly being detected.

aimThe aim of this study was to investigate the rate, impact on treatment, and outcome of unsuspected ISSPE in critically ill patients receiving MDCT. The secondary aim was to investigate the potential impact of contrast media-induced nephropathy (CIN) in our cohort.

methodsWe conducted a retrospective single-centre analysis on critically ill adult patients treated between January 2009 and December 2012 who underwent a contrast-enhanced chest MDCT. We excluded patients with clinical suspicion of PE/ISSPE prior to CT and patients with MDCT confirmed central PE. Clinical findings, laboratory parameters, and outcome data were recorded.

resultsWe identified 240 ICU patients not suspected for PE receiving MDCT. A total of 12 Patients (5%) showed unexpected ISSPE representing increased 24 h mortality (16.7 vs. 3.5%; p = 0.026) compared to non-ISPPE/non-PE patients. A 30-days mortality did not differ between the groups (33.3 vs. 33.8%; p = 0.53). Highest mean creatinine serum level in our cohort (n = 240) was found before MDCT with a significant decrease to day 5 (1.4 ± 1.1 vs. 1.1 ± 0.9 mg/dl: p < 0.0001) after contrast media administration.

conclusionCritically ill patients are at relevant risk for ISSPE. ISSPE was associated with a poor 24 h outcome. In addition, in our cohort, contrast media application was not associated with increased serum creatinine.

Indexed as

AdultAgedAngiographyCohort StudiesContrast MediaCritical CareFemaleHumansIntensive Care UnitsKidney DiseasesLungMaleMiddle AgedPerioperative CarePulmonary EmbolismRetrospective StudiesContrast MediaIntensive care medicineMulti-detector computed tomographic angiographyOutcome predictionSubsegmental pulmonary embolism

Identifiers

PMID26661080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.