Evidence map›Paper›PMID 26660538›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2016

Biological modeling of mucus to modulate mucus barriers.

Jean-Luc Desseyn, Valérie Gouyer, Frédéric Gottrand

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. The Cervicovaginal Mucus Barrier.International journal of molecular sciences · 2020
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jean-Luc DesseynLIRIC-UMR 995, Inserm, University of Lille, Lille, France jean-luc.desseyn@inserm.fr.
Valérie GouyerLIRIC-UMR 995, Inserm, University of Lille, Lille, France.
Frédéric GottrandLIRIC-UMR 995, Inserm, University of Lille, Lille, France.
Inserm · FRLille Inflammation Research International Center · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.

Indexed as

AnimalsGastrointestinal MicrobiomeIntestinal MucosaMucin-2MucusTight JunctionsMucin-2gelling mucinmucin CYS domainmucosal barriermucustransgenic mouse

Identifiers

PMID26660538
OpenAlexW2208975589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.