Evidence map›Paper›PMID 26660468›Full record

ArticleJournal of materials chemistry. B2015

Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment.

E L Lee, H H Bendre, A Kalmykov, J Y Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

E L LeeDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
H H BendreDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
A KalmykovDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
J Y WongDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA ; Department of Materials Science and Engineering, Boston University, Boston, MA 02215, USA.

Funding

Boston University Inflammatory Disorders Training GrantT32AI089673 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WETZLER, LEE MARK · 2011 to 2015
$1.4M
Mechanical Conditioning of Tissue Engineered Blood Vessels for AtherosclerosisF32HL115999 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LEE, ELAINE L · 2012 to 2015
$157k
NHLBI NIH HHS F32 HL115999NIAID NIH HHS T32 AI089673
6 · The paper itself

Abstract

Current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype. We modified a commercially available product for uniaxial cell sheet conditioning with thermoresponsive copolymers. Thus, culture of detachable conditioned cell sheets is shortened while retaining structural integrity and contractility.

Identifiers

PMID26660468
PMCPMC4675169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.