Evidence map›Paper›PMID 26660328›Full record

ArticleMolecular neurobiology2016

Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies.

Grzegorz Satała, Beata Duszyńska, Katarzyna Stachowicz, Anna Rafalo, Bartlomiej Pochwat, Christine Luckhart, Paul R Albert, Mireille Daigle, Kenji F Tanaka, René Hen and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. ZnScientific reports · 2025
    Article
  4. Article
  5. Caged ZnACS chemical neuroscience · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Allosteric Inhibition of Serotonin 5-HTMolecular neurobiology · 2018
    Article
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Grzegorz SatałaInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Beata DuszyńskaInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Katarzyna StachowiczInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Anna RafaloInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Bartlomiej PochwatInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Christine LuckhartOttawa Hospital Research Institute, UOttawa Brain and Mind Research Institute , 451 Smyth Road #2464, Ottawa, ON, K1H-8M5, Canada.
Paul R AlbertOttawa Hospital Research Institute, UOttawa Brain and Mind Research Institute , 451 Smyth Road #2464, Ottawa, ON, K1H-8M5, Canada.
Mireille DaigleOttawa Hospital Research Institute, UOttawa Brain and Mind Research Institute , 451 Smyth Road #2464, Ottawa, ON, K1H-8M5, Canada.
Kenji F TanakaDepartment of Neuropsychiatry, School of Medicine, Keio University, Tokyo, 160-8582, Japan.
René HenDepartment of Psychiatry, Columbia University Medical Center and Research Foundation for Mental Hygiene, New York State Psychiatric Institute, New York, NY, 10032, USA.
Tomasz LendaInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Gabriel NowakInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Andrzej J BojarskiInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland.
Bernadeta SzewczykInstitute of Pharmacology Polish Academy of Sciences , Smetna 12, PL 31-343, Krakow, Poland. szewczyk@if-pan.krakow.pl.
Polish Academy of Sciences · PLMaj Institute of Pharmacology · PLuOttawa Brain and Mind Research InstituteKeio University · JPNew York State Psychiatric InstituteOttawa Hospital · CA

Funding

CIHR 115098-1CIHR 123426-1
6 · The paper itself

Abstract

Recent data has indicated that Zn can modulate serotonergic function through the 5-HT

Indexed as

8-Hydroxy-2-(di-n-propylamino)tetralinAnimalsBehavior, AnimalBody TemperatureHEK293 CellsHumansImmobilizationKineticsMice, KnockoutRats, Sprague-DawleyReceptor, Serotonin, 5-HT1AZinc8-Hydroxy-2-(di-n-propylamino)tetralinReceptor, Serotonin, 5-HT1AZinc5-HT1AAutoreceptorBehavioural studiesBindingDepressionSerotoninZn

Identifiers

PMID26660328
PMCPMC5104769
OpenAlexW2293147610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.