Evidence map›Paper›PMID 26660327›Full record

ArticleMolecular neurobiology2016

Comparison of the Effect of Exercise on Late-Phase LTP of the Dentate Gyrus and CA1 of Alzheimer's Disease Model.

An T Dao, Munder A Zagaar, Amber T Levine, Karim A Alkadhi

Erratum issuedAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Effects of Exercise on Long-Term Potentiation in Neuropsychiatric Disorders.Advances in experimental medicine and biology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

An T DaoDepartment of PPS, College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA.
Munder A ZagaarDepartment of PPS, College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA.
Amber T LevineDepartment of PPS, College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA.
Karim A AlkadhiDepartment of PPS, College of Pharmacy, University of Houston, Houston, TX, 77204-5037, USA. KAlkadhi@uh.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the neuroprotective effect of regular treadmill exercise training on long-term memory and its correlate: the late-phase long-term potentiation (L-LTP) and plasticity- and memory-related signaling molecules in the DG and CA1 areas of a rat model of Alzheimer's disease (AD) (i.c.v. infusion of Aβ

Indexed as

Long-Term PotentiationPhysical Conditioning, AnimalAlzheimer DiseaseAmyloid beta-PeptidesAnimalsBrain-Derived Neurotrophic FactorCA1 Region, HippocampalCalcium-Calmodulin-Dependent Protein Kinase Type 4Cyclic AMP Response Element-Binding ProteinDentate GyrusDisease Models, AnimalMaleMaze LearningMemory DisordersPhosphorylationRats, WistarAmyloid beta-PeptidesBrain-Derived Neurotrophic FactorCalcium-Calmodulin-Dependent Protein Kinase Type 4Cyclic AMP Response Element-Binding ProteinAlzheimer’s diseaseBDNFCA1 areaCaMKIVDentate gyrusExercisefEPSPIn vivo population spike recordingLearningL-LTPLong-term memoryRadial arm water maze

Identifiers

PMID26660327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.