Thioamination of Alkenes with Hypervalent Iodine Reagents.

Pushpak Mizar, Rebecca Niebuhr, Matthew Hutchings, Umar Farooq, Thomas Wirth

Open access · hybridAbstract read

In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

4.7field-weighted citation impact, top 5% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 51 citations in OpenAlex.

Alkene Difunctionalization Using Hypervalent Iodine Reagents: Progress and Developments in the Past Ten Years.Molecules (Basel, Switzerland) · 2019
Review
Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes.Journal of the American Chemical Society · 2018
Article
Enantioselective dioxytosylation of styrenes using lactate-based chiral hypervalent iodine(III).Beilstein journal of organic chemistry · 2018
Article
Rapid transformation of sulfinate salts into sulfonates promoted by a hypervalent iodine(III) reagent.Beilstein journal of organic chemistry · 2018
Article
Synthesis of spirocyclic scaffolds using hypervalent iodine reagents.Beilstein journal of organic chemistry · 2018
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pushpak MizarSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT, UK), Fax.

Rebecca NiebuhrSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT, UK), Fax.

Matthew HutchingsSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT, UK), Fax.

Umar FarooqSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT, UK), Fax.

Thomas WirthSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, CF10 3AT, UK), Fax. wirth@cf.ac.uk.ORCID http://orcid.org/0000-0002-8990-0667

Cardiff University · GBCOMSATS University Islamabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An efficient thioamination of alkenes mediated by iodine(III) reagents is described. The use of different sulfur nucleophiles allows the flexible synthesis of 1,2-aminothiols from alkenes. By employing chiral iodine(III) reagents, a stereoselective version of the thioamination protocol has also been developed.

Indexed as

additionalkenesaminationheterocyclesiodine

Identifiers

PMID26660291

DOI10.1002/chem.201504636

PMCPMC4725223

OpenAlexW2284845980

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.