ArticleGenome biology and evolution2015
Timing and Scope of Genomic Expansion within Annelida: Evidence from Homeoboxes in the Genome of the Earthworm Eisenia fetida.
Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 50 citations in OpenAlex.
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- Annelid Comparative Genomics and the Evolution of Massive Lineage-Specific Genome Rearrangement in Bilaterians.Molecular biology and evolution · 2024Article
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- Gene Loss may have Shaped the Cnidarian and Bilaterian Hox and ParaHox Complement.Genome biology and evolution · 2023Article
- Molecular insights into high-altitude adaption and acclimatisation ofLife science alliance · 2022Article
- A Chromosome-level Genome Assembly of the Highly Heterozygous Sea Urchin Echinometra sp. EZ Reveals Adaptation in the Regulatory Regions of Stress Response Genes.Genome biology and evolution · 2022Article
- Review
- Draft Genome Sequence of the EarthwormCurrent genomics · 2022Article
- Duplication of spiralian-specific TALE genes and evolution of the blastomere specification mechanism in the bivalve lineage.EvoDevo · 2021Article
- Annelid genomes: Enchytraeus crypticus, a soil model for the innate (and primed) immune system.Lab animal · 2021Article
- Amynthas corticis genome reveals molecular mechanisms behind global distribution.Communications biology · 2021Article
- Inferring Tunicate Relationships and the Evolution of the Tunicate Hox Cluster with the Genome of Corella inflata.Genome biology and evolution · 2020Article
- Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration.Nature communications · 2020Article
- High-quality genome assembly ofPeerJ · 2020Article
- Hox gene expression during development of the phoronidEvoDevo · 2020Article
- Sponges Lack ParaHox Genes.Genome biology and evolution · 2019Article
- Draft Genome of the Asian Buffalo LeechFrontiers in genetics · 2019Article
- Data on genome annotation and analysis of earthwormData in brief · 2018Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Annelida represents a large and morphologically diverse group of bilaterian organisms. The recently published polychaete and leech genome sequences revealed an equally dynamic range of diversity at the genomic level. The availability of more annelid genomes will allow for the identification of evolutionary genomic events that helped shape the annelid lineage and better understand the diversity within the group. We sequenced and assembled the genome of the common earthworm, Eisenia fetida. As a first pass at understanding the diversity within the group, we classified 363 earthworm homeoboxes and compared them with those of the leech Helobdella robusta and the polychaete Capitella teleta. We inferred many gene expansions occurring in the lineage connecting the most recent common ancestor (MRCA) of Capitella and Eisenia to the Eisenia/Helobdella MRCA. Likewise, the lineage leading from the Eisenia/Helobdella MRCA to the leech H. robusta has experienced substantial gains and losses. However, the lineage leading from Eisenia/Helobdella MRCA to E. fetida is characterized by extraordinary levels of homeobox gain. The evolutionary dynamics observed in the homeoboxes of these lineages are very likely to be generalizable to all genes. These genome expansions and losses have likely contributed to the remarkable biology exhibited in this group. These results provide a new perspective from which to understand the diversity within these lineages, show the utility of sub-draft genome assemblies for understanding genomic evolution, and provide a critical resource from which the biology of these animals can be studied.
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