Evidence map›Paper›PMID 26659899›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016

Determinants of time trade-off valuations for EQ-5D-5L health states: data from the Canadian EQ-5D-5L valuation study.

Fatima Al Sayah, Nick Bansback, Stirling Bryan, Arto Ohinmaa, Lise Poissant, Eleanor Pullenayegum, Feng Xie, Jeffrey A Johnson

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06396702 (Emotion And Symptom-focused Engagement), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06396702 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Emotion And Symptom-focused Engagement (EASE) Intervention for the Management of Emotional and Physical Symptoms Among Solid Organ Transplant Recipients-pilot Study

TypeinterventionalSponsorUniversity Health Network, TorontoRan2024 to 2027Enrolled120ConditionsTransplant, Failure,Kidney, Transplant, Failure, HeartArmsEASE-SOT
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Preferences for health-related quality of life: do they vary by age? A systematic literature review on the EQ-5D measure.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Pooled it
  2. Factors associated with health state valuations: a secondary analysis of an EQ-5D-3L valuation study from Jordan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Valuation of the EQ-5D-3L in Jordan.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  7. Article
  8. What Makes the Time Tradeoff Tick? A Sociopsychological Explanation.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
    Article
  9. The EQ-5D-5L valuation study for Trinidad and Tobago.Health and quality of life outcomes · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Urban/rural differences in preferences for EQ-5D-5L health states: a study of a multi-ethnic region in China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  14. Article
  15. EQ-5D-5L: a value set for Romania.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  16. Review
  17. Article
  18. Do health preferences differ among Asian populations? A comparison of EQ-5D-5L discrete choice experiments data from 11 Asian studies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  19. Article
  20. Transforming challenges into opportunities: conducting health preference research during the COVID-19 pandemic and beyond.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatima Al Sayah2-040 Li Ka Shing Centre for Health Research Innovation, School of Public Health, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Nick BansbackFaculty of Medicine, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Stirling BryanFaculty of Medicine, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Arto Ohinmaa2-040 Li Ka Shing Centre for Health Research Innovation, School of Public Health, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
Lise PoissantSchool of Rehabilitation, Université de Montréal, Montreal, QC, Canada.
Eleanor PullenayegumChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, ON, Canada.
Feng XieDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
Jeffrey A Johnson2-040 Li Ka Shing Centre for Health Research Innovation, School of Public Health, University of Alberta, Edmonton, AB, T6G 2E1, Canada. jeff.johnson@ualberta.ca.

Funding

Chief Scientist Office HERU1
6 · The paper itself

Abstract

backgroundPrevious studies suggest that population subgroups have different perceptions of health, as well as different preferences for hypothetical health states.

objectiveTo identify determinants of health states preferences elicited using time trade-off (TTO) for the 5-level EQ-5D questionnaire (EQ-5D-5L) in Canada.

methodsData were from the Canadian EQ-5D-5L Valuation Study, which took place in Edmonton, Hamilton, Montreal, and Vancouver. Each respondent valued 10 of 86 hypothetical health states during an in-person interview using a computer-based TTO exercise. The TTO scores were the dependent variable and explanatory variables including age, sex, marital status, education, employment, annual household income, ethnicity, country of birth, dwelling, study site, health literacy, number of chronic conditions, previous experience with illness, and self-rated health.

resultsAverage [standard deviation (SD)] age of respondents (N = 1209) was 48 (17) years, and 45 % were male. In multivariable linear regression models with random effects, adjusted for severity of health states and inconsistencies in valuations, older age [unstandardized regression coefficient (β) = -0.077], male sex (β = 0.042), being married (β = 0.069), and urban dwelling (β = -0.055) were significantly associated with health states scores. Additionally, participants from Edmonton (β = -0.124) and Vancouver (β = -0.156), but not those from Hamilton, had significantly lower TTO scores than those from Montreal.

conclusionsSocio-demographic characteristics were the main determinants of preferences for EQ-5D-5L health states in this study. Interestingly, preferences were significantly lower in western Canadian cities compared to eastern ones, bringing into question whether a single preference algorithm is suitable for use in all parts of Canada.

Indexed as

Health StatusModels, StatisticalPatient PreferenceSurveys and QuestionnairesAdolescentAdultAgedAged, 80 and overCanadaFemaleHumansMaleMiddle AgedPsychometricsSocioeconomic FactorsYoung AdultCanadaEQ-5DHealth preferencesTime trade-off (TTO)

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.