SynthesisHerz2016
Relationship between epicardial adipose tissue volume and atrial fibrillation : A systematic review and meta-analysis.
Synthesis in Herz, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- The Role of Epicardial Adipose Tissue in the Development of Atrial Fibrillation: A Systematic Review and Meta-Analysis.Journal of clinical medicine research · 2026Article
- Potential of Epicardial Adipose Tissue Quantification in Predicting Atrial Thrombus in Patients With Atrial Fibrillation.Reviews in cardiovascular medicine · 2025Article
- Pharmacological and Non-Pharmacological Interventions in Diabetes Mellitus: Effects on Epicardial Adipose Tissue.International journal of molecular sciences · 2025Review
- Epicardial Adipose Tissue Volume Assessment in the General Population and CAD-RADS 2.0 Score Correlation Using Dual Source Cardiac CT.Diagnostics (Basel, Switzerland) · 2025Article
- Imaging biomarkers in cardiac CT: moving beyond simple coronary anatomical assessment.La Radiologia medica · 2024Review
- Impact of Obesity on Atrial Electrophysiological Substrate.Journal of cardiovascular development and disease · 2023Review
- The Different Pathways of Epicardial Adipose Tissue across the Heart Failure Phenotypes: From Pathophysiology to Therapeutic Target.International journal of molecular sciences · 2023Review
- Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue.Anaesthesiology intensive therapy · 2023Article
- Review
- Crosstalk Between Adipose Tissue and the Heart: An Update.Journal of translational internal medicine · 2022Article
- Secretome of atrial epicardial adipose tissue facilitates reentrant arrhythmias by myocardial remodeling.Heart rhythm · 2022Article
- Fat chance for POAF? Pericardial adipose tissue and the arrhythmogenic substrate for postoperative atrial fibrillation.International journal of cardiology. Heart & vasculature · 2022Article
- Novel imaging biomarkers: epicardial adipose tissue evaluation.The British journal of radiology · 2020 · on this mapReview
- The Role of Epicardial Fat in Pericardial Diseases.Current cardiology reports · 2018 · on this mapReview
- The role of epicardial adipose tissue in cardiac biology: classic concepts and emerging roles.The Journal of physiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have suggested that epicardial adipose tissue (EAT) volume may be associated with the risk of atrial fibrillation (AF). However, these studies have reported conflicting results. We therefore aimed to investigate the relationship between EAT volume and AF.
methodsWe systematically retrieved the relevant studies reporting on the relationship between EAT volume and AF using the Cochrane Library, PubMed, Medline, EBSCO, and Embase databases. Data were extracted from applicable articles, and mean differences were pooled using the RevMan 5.3 software.
resultsTen case-control studies were identified. With regard to the relationship between EAT volume and AF, both total-EAT volume (24.23 ml, 95 % CI: 19.40-29.06, p < 0.00001) and EAT volume surrounding the left atrium (LA-EAT; 16.35 ml, 95 %CI: 12.73-19.98, p < 0.00001) were significantly increased in patients with AF. With regard to the relationship between the different types of AF and EAT volume, there was a significant difference in the total-EAT volume subgroup (19.38 ml, 95 % CI: 11.45-27.31, p < 0.0001) and in the LA-EAT volume subgroup (17.91 ml, 95 % CI: 15.13-20.69, p < 0.00001) between patients with persistent AF (PeAF) and paroxysmal AF (PAF). However, there was no significant difference between the total-EAT and LA-EAT volume subgroups (χ (2) = 0.12, p = 0.70).
conclusionEAT volume may be associated with an increased risk of AF. Additionally, the EAT volume in patients with PeAF was larger than that in PAF patients, independent of the location of EAT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.