ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2015
The Behavior of Water in Collagen and Hydroxyapatite Sites of Cortical Bone: Fracture, Mechanical Wear, and Load Bearing Studies.
Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Rapidly Screening the Correlation between the Rotational Mobility and the Hydrogen Bonding Strength of Confined Water.The journal of physical chemistry. B · 2024Article
- 3D Tortuosity and Diffusion Characterization in the Human Mineralized Collagen Fibril Using a Random Walk Model.Bioengineering (Basel, Switzerland) · 2023Article
- Low-field and variable-field NMR relaxation studies of H2O and D2O molecular dynamics in articular cartilage.PloS one · 2021Article
- A computational study of mechanical properties of collagen-based bio-composites.International biomechanics · 2020Article
- Characterization of bony anatomic regions in pediatric and adult healthy volunteers using diffuse optical spectroscopic imaging.Journal of biomedical optics · 2020Article
- Static Solid Relaxation Ordered Spectroscopy: SS-ROSY.International journal of molecular sciences · 2019Article
- Alterations of elastin in female reproductive tissues arising from advancing parity.Archives of biochemistry and biophysics · 2019Article
- Myocardial T1 mapping and extracellular volume quantification: an overview of technical and biological confounders.The international journal of cardiovascular imaging · 2018Review
- Non-destructive NIR spectral imaging assessment of bone water: Comparison to MRI measurements.Bone · 2017Article
- Biosynthetic PCL-graft-Collagen Bulk Material for Tissue Engineering Applications.Materials (Basel, Switzerland) · 2017Article
- Pregnancy-Induced Dynamical and Structural Changes of Reproductive Tract Collagen.Biophysical journal · 2016Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
The mechanical properties of cortical bone, which is largely comprised of collagen, hydroxyapatite, and water, are known to hinge on hydration. Recently, the characteristics of water in bone have drawn attention as potential markers of bone quality. We report on the dynamics, diffusion, population, and exchange of water in cortical bone by NMR relaxation and diffusion methodologies. Relaxation measurements over timescales ranging from 0.001 to 4.2 s reveal two distinguishable water environments. Systematic exposure to ethylenediaminetetraacetic acid or collagenase reveals one peak in our 2D relaxation map belonging to water present in the hydroxyapatite rich environment, and a second peak with shorter relaxation times arising from a collagen rich site. Diffusion-
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.