Evidence map›Paper›PMID 26659492›Full record

ReviewAdvances in experimental medicine and biology2016

Non-coding RNAs in Uterine Development, Function and Disease.

Warren B Nothnick

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
33.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Uterine Fibroids: Hiding in Plain Sight.Physiology (Bethesda, Md.) · 2022
    Review
  11. Review
  12. Review
  13. Understanding the Impact of Uterine Fibroids on Human Endometrium Function.Frontiers in cell and developmental biology · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
  19. TGFβ superfamily signaling and uterine decidualization.Reproductive biology and endocrinology : RB&E · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Warren B NothnickDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, USA. wnothnic@kumc.edu.
University of Kansas Medical Center · US

Funding

The Role of miR-451 in Endometriosis Pathophysiology and TreatmentR01HD069043 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NOTHNICK, WARREN B · 2012 to 2016
$1.7M
Estrogen regulation of uterine microRNAs: Novel factors in MMP-9 regulationR21HD056387 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NOTHNICK, WARREN B · 2007 to 2008
$401k
NICHD NIH HHS HD056387NICHD NIH HHS HD069043NICHD NIH HHS R01 HD069043NICHD NIH HHS R21 HD056387
6 · The paper itself

Abstract

The major function of the uterus is to accept and provide a suitable environment for an embryo, ultimately leading the birth of offspring and successful propagation of the species. For this occur, there must be precise coordination of hormonal signalling within both the endometrial and myometrial components of this organ. Non-coding RNAs, specifically, microRNAs (miRNAs) have been shown to be essential for normal uterine development and function. Within this organ, miRNAs are proposed to fine-tune the actions of the female steroid hormones estradiol and progesterone. Not surprising, mis-expression of miRNAs has been documented in diseases of the endometrium and myometrium such as endometriosis and leiomyomas, respectively. In this chapter, I will review the current understanding on the role, regulation and function of non-coding RNAs focusing on miRNAs in both the normal physiology of the endometrium and myometrium as well as in pathologies of these tissues, namely endometriosis and leiomyomas.

Indexed as

AnimalsEndometriosisEndometriumEstradiolFemaleHumansLeiomyomaMicroRNAsMyometriumProgesteroneRNA, NeoplasmEstradiolMicroRNAsProgesteroneRNA, NeoplasmEndometriosisEndometriumLeiomyomamiRNAMyometriumUterus

Identifiers

PMID26659492
PMCPMC4878440
OpenAlexW2344981296

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.