ReviewClinical & experimental metastasis2016
Management of resectable colorectal lung metastases.
Review in Clinical & experimental metastasis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 59 citations in OpenAlex.
- The Differential Diagnostic Value of Radiomics Signatures Between Single-Nodule Pulmonary Metastases and Second Primary Lung Cancer in Patients with Colorectal Cancer.Technology in cancer research & treatmentTrial
- Intratumoral microbiota in the growth of CRC and lung cancer: Comprehensive insights from etiology to therapy.iScience · 2026Review
- Association between Three-dimensional Margin Assessment and Local Tumor Control in Percutaneous Lung Cryoablation of Colorectal Metastases.Radiology. Imaging cancer · 2026Article
- Predicting lung metastasis after radical colorectal cancer surgery: a two center retrospective cohort study and nomogram development.Frontiers in oncology · 2025Article
- Organotropic metastasis in colorectal cancer: integrating molecular pathways with therapeutic opportunities.Frontiers in immunology · 2025Review
- Surgical Resection of a Solitary Metachronous Retrocaval Lymph Node Metastasis above the Renal Vein from Rectal Cancer.Surgical case reports · 2025Article
- Transvenous Pulmonary Chemoembolization and Optional Microwave Ablation for Colorectal Lung Metastases.Journal of clinical medicine · 2023Article
- Article
- Bronchial or Pulmonary Artery Chemoembolization for Unresectable and Unablatable Lung Metastases: A Phase I Clinical Trial.Radiology · 2021Article
- The impact of primary tumor location on prognosis after colorectal lung metastasectomy.International journal of colorectal disease · 2021Article
- Anatomical Resection Improves Disease-Free Survival After Lung Metastasectomy of Colorectal Cancer.Cancer management and research · 2021Article
- Prognosis of patients with recurrence after pulmonary metastasectomy for colorectal cancer.General thoracic and cardiovascular surgery · 2020Article
- Iodine-125 seed implantation treatment of lung metastases < 2.5 cm using 5-ml syringe as a guide.Journal of contemporary brachytherapy · 2020Article
- A review of interventional treatments for colorectal lung metastases: is it time for a change in practice?Quantitative imaging in medicine and surgery · 2020Article
- Radiotherapy for oligometastatic cancer: a survey among radiation oncologists of Lombardy (AIRO-Lombardy), Italy.La Radiologia medica · 2019Article
- The role of surgical resection before palliative chemotherapy in advanced gastric cancer.Scientific reports · 2019Article
- Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition).Journal of hematology & oncology · 2019Review
- SATB2 Shows Different Profiles Between Appendiceal Adenocarcinomas Ex Goblet Cell Carcinoids and Appendiceal/Colorectal Conventional Adenocarcinomas: An Immunohistochemical Study With Comparison to CDX2.Gastroenterology research · 2018Article
- Value of ablation therapy in the treatment of lung metastases.Thoracic cancer · 2018Review
- Herbal compound Teng-Long-Bu-Zhong-Tang inhibits metastasis in human RKO colon carcinoma.Oncology letters · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung metastases occur in 10-20 % of patients with colorectal cancer. The biology of colorectal lung metastases is poorly understood, however lung metastases are more common in patients with rectal cancer and in patients with RAS mutations. Although the majority of patients have extrapulmonary disease, a small proportion of patients with lung metastases are suitable for lung metastasectomy and surgical resection has become a standard of care, based on data from retrospective series demonstrating a 5-year overall survival of 40-68 %. However, there remains uncertainty regarding the optimal management approach for these patients due to the lack of evidence from randomized controlled trials and current practice varies between institutions. For example, the role for neoadjuvant and adjuvant chemotherapy is not yet defined and there are no randomized trials comparing surgery with alternative treatment options such as radiofrequency ablation and stereotactic ablative radiotherapy. Further research is needed to improve the selection of patients for surgery, but favourable prognostic factors include a normal pre-operative CEA, solitary metastasis, complete resection and a long disease-free interval. There is also evidence that patients with resectable liver and lung metastases may benefit from resection of both sites of disease, and that re-resection may be of benefit in selected patients who relapse with resectable lung metastases. This article summarizes the biology of colorectal lung metastases and discusses the management of patients with lung metastases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.