Evidence map›Paper›PMID 26659238›Full record

ArticleSurgical endoscopy2016

Significance of Nissen fundoplication after endoscopic radiofrequency ablation of Barrett's esophagus.

Ognjan Skrobić, Aleksandar Simić, Nebojša Radovanović, Nenad Ivanović, Marjan Micev, Predrag Peško

Abstract read
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Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Barrett's Esophagus: An Updated Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  4. Unmet needs in Barret's esophagus diagnosis and treatment: a narrative review.Translational gastroenterology and hepatology · 2023
    Review
  5. LAPAROSCOPIC ANTIREFLUX SURGERY: ARE OLD QUESTIONS ANSWERED? SHOULD IT BE USED CONJOINED WITH ENDOSCOPIC THERAPY FOR BARRETT'S ESOPHAGUS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
  6. Review
  7. Challenges in Endoscopic Therapy of Dysplastic Barrett's Esophagus.Current treatment options in gastroenterology · 2019
    Review
  8. Article
  9. Precision care for Barrett's esophagus.Translational gastroenterology and hepatology · 2018
    Review
  10. Review
  11. Advances in the Diagnosis and Treatment of Barrett's Esophagus and Early Esophageal Cancer; Summary of the Kelly and Carlos Pellegrini SSAT/SAGES Luncheon Symposium.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Review
  12. Barrett's esophagus: diagnosis and management.Gastrointestinal endoscopy · 2017
    Review
  13. Observational
  14. Update on the management of Barrett's esophagus in Austria.European surgery : ACA : Acta chirurgica Austriaca · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ognjan SkrobićDepartment of Esophageal Surgery, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Koste Todorovica St 6, Belgrade, 11 000, Serbia. skrobico@gmail.com.
Aleksandar SimićDepartment of Esophageal Surgery, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Koste Todorovica St 6, Belgrade, 11 000, Serbia.
Nebojša RadovanovićDepartment of Esophageal Surgery, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Koste Todorovica St 6, Belgrade, 11 000, Serbia.
Nenad IvanovićDepartment of Esophageal Surgery, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Koste Todorovica St 6, Belgrade, 11 000, Serbia.
Marjan MicevDepartment of Digestive Pathology, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Belgrade, Serbia.
Predrag PeškoDepartment of Esophageal Surgery, Clinical Center of Serbia, School of Medicine, First Surgical University Hospital, University of Belgrade, Koste Todorovica St 6, Belgrade, 11 000, Serbia.
University of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHALO radiofrequency ablation (RFA) has been proven as safe and efficient in eradication of both non- and dysplastic Barrett's esophagus (BE). Definitive post-RFA treatment is yet to be determined.

methodsRFA was performed in 56 patients with BE, 38 with intestinal metaplasia (IM) and 18 with low-grade dysplasia (LGD), and repeated in case of residual BE. Length of the BE was classified according to C&M criteria. Follow-up included regular upper GI endoscopies with biopsies 6 months, 1 and 2 years after the complete resolution of BE. Patients were divided into two groups regarding post-RFA treatment: those maintaining proton pump inhibitors (PPI) daily and those submitted to laparoscopic Nissen fundoplication (LNF) at least 3 months after BE eradication or synchronous with RFA.

resultsThere were no perforations or strictures related to RFA. Complete endoscopic resolution of BE was observed in 83.92 % patients (86.84 % IM and 77.77 % LGD), in 25 that maintained PPI and 22 in whom LNF was done. In PPI group, 2-year follow-up revealed BE recurrence in biopsy samples in 20 % of patients, while in LNF group 9.1 % of patients had recurrent IM. In overall sample of patients, no difference was noted regarding the influence of post-RFA treatment (p < 0.423). LNF proved superiority over PPI treatment in patients with long-segment BE (cutoff C > 4 cm, p < 0.021).

conclusionHALO RFA is a safe procedure, with high rate of success in complete eradication of BE in symptomatic GERD patients. LNF provides good protection for neosquamous epithelium and in selected group of patients could be offered as a first line of treatment after HALO RFA.

Indexed as

AdultAgedBarrett EsophagusCatheter AblationEndoscopy, Digestive SystemFemaleFundoplicationHumansMaleMiddle AgedOutcome Assessment, Health CareProton Pump InhibitorsRecurrenceProton Pump InhibitorsBarrett’s esophagusLaparoscopic Nissen fundoplicationRadiofrequency ablation

Identifiers

PMID26659238
OpenAlexW2193376777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.