SynthesisSurgical endoscopy2016
Comparison of endoscopic resection and gastrectomy for the treatment of early gastric cancer: a meta-analysis.
Synthesis in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Survival benefits of additional surgery after non-curative endoscopic resection in patients with early gastric cancer: a meta-analysis.Surgical endoscopy · 2019Pooled it
- Long-Term Outcomes Comparison of Endoscopic Resection With Gastrectomy for Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Multimodal Transformer-Based Preoperative Risk Assessment of Lymph Node Metastasis in Early Gastric Cancer Using Whole Slide Images of Endoscopic Biopsies.Annals of biomedical engineering · 2026Article
- The Impact of Institutional Volume of Endoscopic Resection on Early-Stage Gastric Cancer Outcomes.Journal of surgical oncology · 2026Article
- Integration of clinical, pathological, and endoscopic data improves prediction for lymph node metastasis in early gastric cancer: a retrospective multicenter study.International journal of surgery (London, England) · 2026Article
- Metachronous gastric neoplasm beyond 5 years after endoscopic resection for early gastric cancer.Surgical endoscopy · 2023Article
- Descriptive Analysis of Gastric Cancer Mortality in Korea, 2000-2020.Cancer research and treatment · 2023Article
- Lymph node involvement in gastric adenocarcinoma.Surgical endoscopy · 2022Article
- Outcomes of simultaneous endoscopic submucosal dissection for synchronous multiple gastric neoplastic lesions: a retrospective comparative study.Surgical endoscopy · 2022Article
- Endoscopic or Follow-up Treatment for Gastric Indeterminate Tumors Is the Preferred Method of Management.Frontiers in oncology · 2022Article
- GIST of the stomach masquerading as recurrent falls in an older adult: a case report and review.BMC gastroenterology · 2021Article
- Endoscopic Submucosal Dissection versus Surgery for Undifferentiated-Type Early Gastric Cancer: A Systematic Review and Meta-Analysis.Clinical endoscopy · 2021Article
- Nomograms for Predicting the Lymph Node Metastasis in Early Gastric Cancer by Gender: A Retrospective Multicentric Study.Frontiers in oncology · 2021Article
- Article
- Effect and cost-effectiveness of national gastric cancer screening in Japan: a microsimulation modeling study.BMC medicine · 2020Article
- [Pneumothorax Following Gastric Endoscopic Mucosal Resection].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020Article
- Long-term outcomes of endoscopic submucosal dissection versus surgery for treating early gastric cancer of undifferentiated-type.Medicine · 2020Article
- Current surgical treatment of esophagogastric junction adenocarcinoma.World journal of gastrointestinal oncology · 2019Review
- Comparison of endoscopic submucosal dissection with surgical gastrectomy for early gastric cancer: An updated meta-analysis.World journal of gastrointestinal oncology · 2019Article
- Expression of macrophage inhibitory cytokine-1 in early gastric cancer cases treated using endoscopic mucosal resection and the correlation with prognosis.Oncology letters · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic resection methods, including endoscopic mucosal resection and endoscopic submucosal dissection, have become standard treatment modalities for patients with early gastric cancer (EGC) and absolute indications, with en bloc resection being more frequent with the latter. Endoscopic resection, however, has been associated with higher recurrence and metachronous cancer rates than gastrectomy. This meta-analysis compared the efficacy and safety of endoscopic resection and gastrectomy for EGC.
methodsPubMed, EMBASE and Web of Science were electronically searched for relevant studies comparing endoscopic resection and gastrectomy for EGC from 1976 through March 2015. The primary endpoints were en bloc resection and histologically complete resection rates. The secondary endpoints were duration of hospital stay and rates of complications, recurrence, metachronous cancer and overall survival.
resultsThis meta-analysis enrolled 10 studies with 2070 patients: 993 patients who underwent endoscopic resection and 1077 who underwent gastrectomy. Endoscopic resection was associated with shorter hospital stay (standardized mean difference -2.02; 95 % confidence interval [CI] -2.64 to -1.39) and lower complication rate (relative risk [RR] 0.41; 95 % CI 0.22-0.76) than gastrectomy. However, endoscopic resection was associated with lower rates of en bloc resection (odds ratio [OR] 0.05; 95 % CI 0.02-0.16) and histologically complete resection (OR 0.04; 95 % CI 0.01-0.11) and higher rates of recurrence (RR 5.23; 95 % CI 2.43-11.27) and metachronous cancer (RR 5.22; 95 % CI 2.40-11.34) than gastrectomy. Overall survival rate (OR 1.18; 95 % CI 0.76-1.82) was similar.
conclusionsEndoscopic resection is minimally invasive and as effective as surgery, suggesting that the former be considered standard treatment for EGC. It should be recommended as standard treatment for EGC with indications. Additional randomized controlled trials from more countries are required.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.