Evidence map›Paper›PMID 26659219›Full record

ReviewJournal of clinical microbiology2016

Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection.

Gavin Cloherty, Andrew Talal, Kelly Coller, Corklin Steinhart, John Hackett, George Dawson, Juergen Rockstroh, Jordan Feld

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03025074 (Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03025074 recruitingnot on this map

Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases

Typeobservational_patient_registrySponsorState University of New York at BuffaloRan2013 to 2099Enrolled1,000ConditionsNon-Alcoholic Steatohepatitis(NASH), Hepatitis C, Hepatitis B, Fibrosis
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  6. Article
  7. Review
  8. A Cost-Effectiveness Analysis of Shortened Direct-Acting Antiviral Treatment in Genotype 1 Noncirrhotic Treatment-Naive Patients With Chronic Hepatitis C Virus.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gavin ClohertyAbbott Diagnostics, Abbott Park, Illinois, USA gavin.cloherty@abbott.com.
Andrew TalalUniversity at Buffalo, Buffalo, New York, USA.
Kelly CollerAbbott Diagnostics, Abbott Park, Illinois, USA.
Corklin SteinhartViiV Healthcare, Research Triangle Park, North Carolina, USA.
John HackettAbbott Diagnostics, Abbott Park, Illinois, USA.
George DawsonAbbott Diagnostics, Abbott Park, Illinois, USA.
Juergen RockstrohUniversity Bonn, Bonn, Germany.
Jordan FeldUniversity of Toronto, Toronto, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs. This review gives an overview on the role of HCV infection diagnostic testing (molecular and serological tools) used in the diagnosis and management of HCV infection. All of this critical information guides physician decisions to optimize patient clinical outcomes. Also discussed is the future direction of diagnostic testing in the context of further advances in drug development.

Indexed as

Molecular Diagnostic TechniquesSerologic TestsAcute DiseaseAntigens, ViralAntiviral AgentsDisease ManagementDrug Resistance, ViralGenotypeHepacivirusHepatitis CHepatitis C, ChronicHumansMedication AdherenceMicrobial Sensitivity TestsRNA, ViralTreatment OutcomeAntigens, ViralAntiviral AgentsRNA, Viral

Identifiers

PMID26659219
PMCPMC4733206

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.