Evidence map›Paper›PMID 26658938›Full record

Trial reportPLoS neglected tropical diseases2015

Assessment of a Novel Approach to Identify Trichiasis Cases Using Community Treatment Assistants in Tanzania.

Gregory S Greene, Sheila K West, Harran Mkocha, Beatriz Munoz, Shannath L Merbs

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Trachoma.Nature reviews. Disease primers · 2022
    Review
  5. Review
  6. Piloting a trachomatous trichiasis patient case-searching approach in two localities of Sudan.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2020
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gregory S GreeneDana Center for Preventative Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Sheila K WestDana Center for Preventative Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Harran MkochaKongwa Trachoma Project, Kongwa, United Republic of Tanzania.
Beatriz MunozDana Center for Preventative Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Shannath L MerbsThe Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

Funding

Surveillance & Treatment of Community Newcomers & Travelers for Trachoma ControlU10EY022584 · NEI · JOHNS HOPKINS UNIVERSITY · PI WEST, SHEILA K · 2012 to 2015
$4.5M
NEI NIH HHS U10 EY022584
6 · The paper itself

Abstract

backgroundSimple surgical intervention advocated by the World Health Organization can alleviate trachomatous trichiasis (TT) and prevent subsequent blindness. A large backlog of TT cases remain unidentified and untreated. To increase identification and referral of TT cases, a novel approach using standard screening questions, a card, and simple training for Community Treatment Assistants (CTAs) to use during Mass Drug Administration (MDA) was developed and evaluated in Kongwa District, a trachoma-endemic area of central Tanzania. METHODOLOGY/PRINCIPAL

findingsA community randomized trial was conducted in 36 communities during MDA. CTAs in intervention villages received an additional half-day of training and a TT screening card in addition to the training received by CTAs in villages assigned to usual care. All MDA participants 15 years and older were screened for TT, and senior TT graders confirmed case status by evaluating all screened-positive cases. A random sample of those screened negative for TT and those who did not present at MDA were also evaluated by the master graders. Intervention CTAs identified 5.6 times as many cases (n = 50) as those assigned to usual care (n = 9, p < 0.05). While specificity was above 90% for both groups, the sensitivity for the novel screening tool was 31.2% compared to 5.6% for the usual care group (p < 0.05). CONCLUSIONS/SIGNIFICANCE: CTAs appear to be viable resources for the identification of TT cases. Additional training and use of a TT screening card significantly increased the ability of CTAs to recognize and refer TT cases during MDA; however, further efforts are needed to improve case detection and reduce the number of false positive cases.

Indexed as

Community Health WorkersHealth Services ResearchAdolescentAdultAgedAged, 80 and overAnti-Infective AgentsEducation, MedicalFemaleHumansMaleMass ScreeningMedical History TakingMiddle AgedSurveys and QuestionnairesTanzaniaAnti-Infective Agents

Identifiers

PMID26658938
PMCPMC4676626

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.