Evidence map›Paper›PMID 26658899›Full record

Trial reportEuropean journal of nutrition2017

Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained females.

Jordan M Glenn, Michelle Gray, Lauren N Wethington, Matthew S Stone, Rodger W Stewart, Nicole E Moyen

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 5 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 80 citations in OpenAlex.

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  12. Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adultsJournal of the International Society of Sports Nutrition · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jordan M GlennOffice for Studies on Aging - University of Arkansas, Fayetteville, AR, USA. jmglenn@latech.edu.
Michelle GrayOffice for Studies on Aging - University of Arkansas, Fayetteville, AR, USA.
Lauren N WethingtonOffice for Studies on Aging - University of Arkansas, Fayetteville, AR, USA.
Matthew S StoneOffice for Studies on Aging - University of Arkansas, Fayetteville, AR, USA.
Rodger W StewartOffice for Studies on Aging - University of Arkansas, Fayetteville, AR, USA.
Nicole E MoyenHuman Performance Lab - University of Arkansas, Fayetteville, AR, USA.
University of Arkansas at Fayetteville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCitrulline malate (CM) is a nonessential amino acid that increases exercise performance in males. However, based on physiological differences between genders, these results cannot be extrapolated to females. Therefore, the purpose of this investigation was to evaluate effects of acute CM supplementation on upper- and lower-body weightlifting performance in resistance-trained females.

methodsFifteen females (23 ± 3 years) completed two randomized, double-blind trials consuming either CM (8 g dextrose + 8 g CM) or a placebo (8 g dextrose). One hour after supplement consumption, participants performed six sets each of upper- (i.e., bench press) and lower-body (i.e., leg press) exercises to failure at 80 % of previously established one-repetition maximum. Immediately after each set, repetitions completed, heart rate and rating of perceived exertion (RPE) were recorded.

resultsRepeated-measures analysis of variance indicated that subjects completed significantly (p = .045) more repetitions throughout upper-body exercise when consuming CM versus placebo (34.1 ± 5.7 vs. 32.9 ± 6.0, respectively). When consuming CM, similar significant (p = .03) improvements in total repetitions completed were observed for lower-body exercise (66.7 ± 30.5 vs. 55.13 ± 20.64, respectively). Overall RPE score was significantly lower (p = .02) in upper-body exercise when subjects consumed CM versus placebo (7.9 ± 0.3 and 8.6 ± 0.2, respectively). The supplement consumed exhibited no significant effects on heart rate at any time point.

conclusionsAcute CM supplementation in females increased upper- and lower-body resistance exercise performance and decreased RPE during upper-body exercise. These data indicate that athletes competing in sports with muscular endurance-based requirements may potentially improve performance by acutely supplementing CM.

Indexed as

Athletic PerformanceDietary SupplementsSports Nutritional Physiological PhenomenaWeight LiftingAdultAthletesCitrullineCross-Over StudiesDouble-Blind MethodFatigueFemaleHeart RateHumansMalatesMuscle, SkeletalPerformance-Enhancing SubstancesCitrullinecitrulline malateMalatesPerformance-Enhancing SubstancesAmino acidsErgogenic aidNitric oxideResistance exerciseSports nutritionWomen

Identifiers

PMID26658899
OpenAlexW2195488794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.