Observational studyBMJ quality & safety2016
Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study.
Observational study in BMJ quality & safety, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Pre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- Outcomes of in-hospital cardiac arrests during and after office hours in a single tertiary centre in Singapore.Singapore medical journal · 2026Article
- Disparities in Survival After In-Hospital Cardiac Arrest by Time of Day and Day of Week: A Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Influence of day-night and weekday-weekend differences on rapid response team performance in in-hospital cardiac arrest.Revista da Associacao Medica Brasileira (1992) · 2026Observational
- Just-in-Time Simulation Training to Augment Overnight ICU Resident Education.Journal of graduate medical education · 2024Article
- A Retrospective Analysis of Characteristics Favouring In-Hospital Resuscitation Plan Completion, Their Timing, and Associated Outcomes.Journal of clinical medicine · 2024Article
- Effects of circadian rhythm on Narcotrend index and target-controlled infusion concentration of propofol anesthesia.BMC anesthesiology · 2021Observational
- Use of simulation as a needs assessment to develop a focused team leader training curriculum for resuscitation teams.Advances in simulation (London, England) · 2020Article
- Predicting Outcomes of In-Hospital Cardiac Arrest: Retrospective US Validation of the Good Outcome Following Attempted Resuscitation Score.Journal of general internal medicine · 2019Observational
- The weekend effect revisited: evidence from the Upper Austrian stroke registry.The European journal of health economics : HEPAC : health economics in prevention and care · 2019Article
- Weekend admissions may be associated with poorer recording of long-term comorbidities: a prospective study of emergency admissions using administrative data.BMC health services research · 2018Article
- Impact of out-of-hours admission on patient mortality: longitudinal analysis in a tertiary acute hospital.BMJ quality & safety · 2018Article
- Impact of intervention time on hospital survival in patients requiring emergent airway management: a preliminary study.Journal of anesthesia · 2018Article
- Effects of night-time and weekend admissions on in-hospital mortality in acute myocardial infarction patients in Japan.PloS one · 2018Article
- Association Between Survival and Time of Day for Rapid Response Team Calls in a National Registry.Critical care medicine · 2017Article
- Arrival by ambulance explains variation in mortality by time of admission: retrospective study of admissions to hospital following emergency department attendance in England.BMJ quality & safety · 2017Article
- Observational
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInternationally, hospital survival is lower for patients admitted at weekends and at night. Data from the UK National Cardiac Arrest Audit (NCAA) indicate that crude hospital survival was worse after in-hospital cardiac arrest (IHCA) at night versus day, and at weekends versus weekdays, despite similar frequency of events.
objectiveTo describe IHCA demographics during three day/time periods-weekday daytime (Monday to Friday, 08:00 to 19:59), weekend daytime (Saturday and Sunday, 08:00 to 19:59) and night-time (Monday to Sunday, 20:00 to 07:59)-and to compare the associated rates of return of spontaneous circulation (ROSC) for >20 min (ROSC>20 min) and survival to hospital discharge, adjusted for risk using previously developed NCAA risk models. To consider whether any observed difference could be attributed to differences in the case mix of patients resident in hospital and/or the administered care.
methodsWe performed a prospectively defined analysis of NCAA data from 27 700 patients aged ≥16 years receiving chest compressions and/or defibrillation and attended by a hospital-based resuscitation team in response to a resuscitation (2222) call in 146 UK acute hospitals.
resultsRisk-adjusted outcomes (OR (95% CI)) were worse (p<0.001) for both weekend daytime (ROSC>20 min 0.88 (0.81 to 0.95); hospital survival 0.72 (0.64 to 0.80)), and night-time (ROSC>20 min 0.72 (0.68 to 0.76); hospital survival 0.58 (0.54 to 0.63)) compared with weekday daytime. The effects were stronger for non-shockable than shockable rhythms, but there was no significant interaction between day/time of arrest and age, or day/time of arrest and arrest location. While many daytime IHCAs involved procedures, restricting the analyses to IHCAs in medical admissions with an arrest location of ward produced results that are broadly in line with the primary analyses.
conclusionsIHCAs attended by the hospital-based resuscitation team during nights and weekends have substantially worse outcomes than during weekday daytimes. Organisational or care differences at night and weekends, rather than patient case mix, appear to be responsible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.