ArticlePloS one2015
Multiscale Entropy of Electroencephalogram as a Potential Predictor for the Prognosis of Neonatal Seizures.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Trial
- Observational
- Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data.Pediatric research · 2025Article
- Computational EEG attributes predict response to therapy for epileptic spasms.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Epileptic spasms relapse is associated with response latency but not conventional attributes of post-treatment EEG.Epilepsia open · 2024Article
- Signal complexity indicators of health status in clinical EEG.Scientific reports · 2021Article
- Measuring the effects of sleep on epileptogenicity with multifrequency entropy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Changes in EEG permutation entropy in the evening and in the transition from wake to sleep.Sleep · 2021Article
- Brain Dynamics Altered by Photic Stimulation in Patients with Alzheimer's Disease and Mild Cognitive Impairment.Entropy (Basel, Switzerland) · 2021Article
- Spatiotemporal Integrity and Spontaneous Nonlinear Dynamic Properties of the Salience Network Revealed by Human Intracranial Electrophysiology: A Multicohort Replication.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Article
- Impact of local thermal stimulation on the correlation between oxygen saturation and speed-resolved blood perfusion.Scientific reports · 2020Article
- Resting-state brain entropy in right temporal lobe epilepsy and its relationship with alertness.Brain and behavior · 2019Article
- Evaluation of the efficacy of amplitude-integrated electroencephalography in the screening of newborns with metabolic disorder admitted to the NICU.BMC medical imaging · 2018Article
- A Feature Extraction Method Using Improved Multi-Scale Entropy for Rolling Bearing Fault Diagnosis.Entropy (Basel, Switzerland) · 2018Article
- Preoperative Heart Rate Variability as Predictors of Vagus Nerve Stimulation Outcome in Patients with Drug-resistant Epilepsy.Scientific reports · 2018Article
- Dynamic Complexity of Spontaneous BOLD Activity in Alzheimer's Disease and Mild Cognitive Impairment Using Multiscale Entropy Analysis.Frontiers in neuroscience · 2018Article
- Sample Entropy on Multidistance Signal Level Difference for Epileptic EEG Classification.TheScientificWorldJournal · 2018Article
- Complexity of brain signals is associated with outcome in preterm infants.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIncreasing animal studies supported the harmful effects of prolonged or frequent neonatal seizures in developing brain, including increased risk of later epilepsy. Various nonlinear analytic measures had been applied to investigate the change of brain complexity with age. This study focuses on clarifying the relationship between later epilepsy and the changes of electroencephalogram (EEG) complexity in neonatal seizures.
methodsEEG signals from 19 channels of the whole brain from 32 neonates below 2 months old were acquired. The neonates were classified into 3 groups: 9 were normal controls, 9 were neonatal seizures without later epilepsy, and 14 were neonatal seizures with later epilepsy. Sample entropy (SamEn), multiscale entropy (MSE) and complexity index (CI) were analyzed.
resultsAlthough there was no significant change in SamEn, the CI values showed significantly decreased over Channels C3, C4, and Cz in patients with neonatal seizures and later epilepsy compared with control group. More multifocal epileptiform discharges in EEG, more abnormal neuroimaging findings, and higher incidence of future developmental delay were noted in the group with later epilepsy.
conclusionsDecreased MSE and CI values in patients with neonatal seizures and later epilepsy may reflect the mixed effects of acute insults, underlying brain immaturity, and prolonged seizures-related injuries. The analysis of MSE and CI can therefore provide a quantifiable and accurate way to decrypt the mystery of neonatal seizures, and could be a promising predictor.
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