Evidence map›Paper›PMID 26658269›Full record

ArticleThe Journal of international medical research2016

Application of spectral computed tomography dual-substance separation technology for diagnosing left ventricular thrombus.

Hong Zeng, Meng-Chao Zhang, Yu-Quan He, Lin Liu, Ya-Liang Tong, Ping Yang

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Cardiac CT for electrophysiological interventions.The international journal of cardiovascular imaging · 2025
    Review
  2. Review
  3. Review
  4. Pre- and post-procedural cardiac imaging (computed tomography and magnetic resonance imaging) in electrophysiology: a clinical consensus statement of the European Heart Rhythm Association and European Association of Cardiovascular Imaging of the European Society of Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Image-domain Material Decomposition for Spectral CT using a Generalized Dictionary Learning.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  9. Management of left ventricular thrombus: a narrative review.Annals of translational medicine · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hong ZengDivision of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Meng-Chao ZhangDivision of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Yu-Quan HeDivision of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Lin LiuDivision of Radiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Ya-Liang TongDivision of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Ping YangDivision of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China pyang@jlu.edu.cn.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the value of spectral computed tomography (CT) dual-substance separation technology for diagnosing left ventricular (LV) thrombus.

methodsIn this observational case-control study, spectral CT scans were conducted in patients with and without LV thrombi. Densities in the regions of the LV cavity, papillary muscles and LV thrombus were observed on 140 kVp mixed-energy and 70 keV single-energy images. Iodine and blood were chosen as the base material pair, the densities were observed and the iodine and blood concentrations were quantitatively measured.

resultsA total of 24 patients were enrolled in this study. On iodine-based density images, both the LV thrombus and papillary muscles showed low-attenuation shadows. On blood-based density images, comparable high-density attenuation was found in the LV thrombus and LV cavity, while relative hypodensity was noted in the papillary muscles. Iodine and blood densities were significantly lower in papillary muscles than in the LV cavity. Iodine densities were significantly lower in the LV thrombus than the LV cavity, whereas blood densities in the two areas did not differ significantly.

conclusionsSpectral CT dual-substance separation technology and its derived images of iodine- and blood- based densities provide a new, simple, and feasible semiquantitative method to detect LV thrombus that warrants further investigation.

Indexed as

AdultAgedContrast MediaFemaleHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedThrombosisTomography, X-Ray ComputedContrast Medialeft ventriclespectral imagingThrombosistomographyX-radiography computer

Identifiers

PMID26658269
PMCPMC5536565
OpenAlexW2195311957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.