ReviewSeminars in cell & developmental biology2016
Towards a predictive model of chromatin 3D organization.
Review in Seminars in cell & developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Architectural transcription factors collectively shape nuclear radial positioning of chromatin contacts.Science advances · 2025Article
- Machine and Deep Learning Methods for Predicting 3D Genome Organization.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Footprint-C reveals transcription factor modes in local clusters and long-range chromatin interactions.Nature communications · 2024Article
- Article
- Computational approaches for inferring 3D conformations of chromatin from chromosome conformation capture data.Methods (San Diego, Calif.) · 2020Review
- Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation.Nature communications · 2020Article
- 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells.PLoS genetics · 2017Article
- An intrinsic mechanism controls reactivation of neural stem cells by spindle matrix proteins.Nature communications · 2017Article
- Genomic landscape of CpG rich elements in human.BMC evolutionary biology · 2017Article
- Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.Genome biology · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Architectural proteins mediate interactions between distant regions in the genome to bring together different regulatory elements while establishing a specific three-dimensional organization of the genetic material. Depletion of specific architectural proteins leads to miss regulation of gene expression and alterations in nuclear organization. The specificity of interactions mediated by architectural proteins depends on the nature, number, and orientation of their binding site at individual genomic locations. Knowledge of the mechanisms and rules governing interactions among architectural proteins may provide a code to predict the 3D organization of the genome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.