Evidence map›Paper›PMID 26658025›Full record

ArticlePreventive medicine2016

Racial-ethnic disparities in the association between risk factors and diabetes: The Northern Manhattan Study.

Erin R Kulick, Yeseon P Moon, Ken Cheung, Joshua Z Willey, Ralph L Sacco, Mitchell S V Elkind

Abstract read
In one paragraph

Article in Preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  7. C-reactive Protein and Racial Differences in Type 2 Diabetes Incidence: The REGARDS Study.The Journal of clinical endocrinology and metabolism · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Erin R KulickDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. Electronic address: erk2140@cumc.columbia.edu.
Yeseon P MoonDepartment of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Ken CheungDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Joshua Z WilleyDepartment of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Ralph L SaccoDepartment of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA; Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA; Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Mitchell S V ElkindDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Columbia University · USColumbia University Irving Medical Center · USUniversity of Miami · US

Funding

STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGIONR01NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 1993 to 2019
$19.2M
Stroke Incidence and Risk Factors in a Tri-Ethnic RegionR37NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 2008 to 2014
$12.1M
NINDS NIH HHS R01 NS029993NINDS NIH HHS R37 NS029993NINDS NIH HHS R37 NS29993
6 · The paper itself

Abstract

purposeTo identify risk factors (RF) for diabetes within a multiethnic cohort and to examine whether race-ethnicity modified their effects.

methodsParticipants in the Northern Manhattan Study without diabetes at baseline were studied from 1993 to 2014 (n=2430). Weibull regression models with interval censoring data were fit to calculate hazard ratios and 95% confidence intervals for incident diabetes. We tested for interactions between RF and race-ethnicity.

resultsDuring a mean follow-up period of 11years, there were 449 diagnoses of diabetes. Being non-Hispanic black (HR 1.69 95% CI 1.11-2.59) or Hispanic (HR 2.25 95% CI 1.48-3.40) versus non-Hispanic white, and body mass index (BMI; HR 1.34 per SD 95% CI 1.21-1.49) were associated with greater risk of diabetes; high-density lipoprotein cholesterol (HR 0.75 95% CI 0.66-0.86) was protective. There were interactions by race-ethnicity. In stratified models, the effects of BMI, current smoking, and C-reactive protein (CRP) on risk of diabetes differed by race-ethnicity (p for interaction <0.05). The effects were greater among non-Hispanic whites than non-Hispanic blacks and Hispanics.

conclusionsAlthough Hispanics and non-Hispanic blacks had a greater risk of diabetes than whites, there were variations by race-ethnicity in the association of BMI, smoking, and CRP with risk of diabetes. Unique approaches should be considered to reduce diabetes as traditional RF may not be as influential in minority populations.

Indexed as

EthnicityHealth Status DisparitiesRacial GroupsAgedBlack or African AmericanBody Mass IndexC-Reactive ProteinDiabetes Mellitus, Type 2FemaleHispanic or LatinoHumansMaleMiddle AgedNew York CityProspective StudiesRisk FactorsC-Reactive ProteinDiabetes mellitusEpidemiologyHealth status disparitiesRisk factorsUrban health

Identifiers

PMID26658025
PMCPMC4724287
OpenAlexW2191513696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.