ArticleJournal of pathology and translational medicine2016
Meningeal Solitary Fibrous Tumors with Delayed Extracranial Metastasis.
Article in Journal of pathology and translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- A review of solitary fibrous tumor/hemangiopericytoma tumor and a comparison of risk factors for recurrence, metastases, and death among patients with spinal and intracranial tumors.Neurosurgical review · 2021Pooled it
- Surveillance for metastatic hemangiopericytoma-solitary fibrous tumors-systematic literature review on incidence, predictors and diagnosis of extra-cranial disease.Journal of neuro-oncology · 2018Pooled it
- A Rare Case of Distant Intradural Extramedullary Thoracic Metastasis from an Intracranial Solitary Fibrous Tumor.Spine surgery and related research · 2026Article
- Solitary fibrous tumor of the posterior fossa: a rare and atypical case report.International journal of surgery case reports · 2026Article
- The association between WHO grading and the long-term outcomes and radiotherapy efficacy of intracranial solitary fibrous tumors.Acta neuropathologica communications · 2025Article
- Meningeal malignant solitary fibrous tumor with multiple recurrence, extracranial extension, cervical lymph node metastases: case report and review of the literature.Discover oncology · 2025Article
- A Case of Intracranial Solitary Fibrous Tumor Followed by Distant Metastasis without Local Recurrence.NMC case report journal · 2025Article
- Article
- Multidisciplinary Treatment of Liver Metastases from Intracranial SFTs/HPCs: A Report of Three Consecutive Cases.Current oncology (Toronto, Ont.) · 2022Article
- Cerebral Hemangiopericytoma Manifesting as Epilepsia Partialis Continua: A Case Report.JNMA; journal of the Nepal Medical Association · 2022Article
- Stereotactic radiosurgery for sellar solitary fibrous tumors: Case report and literature review.Journal of radiosurgery and SBRT · 2022Article
- Article
- Solitary fibrous tumor of the pineal region with delayed ectopic intracranial metastasis: A case report and review of the literature.Medicine · 2019Article
- Grading of meningeal solitary fibrous tumors/hemangiopericytomas: analysis of the prognostic value of the Marseille Grading System in a cohort of 132 patients.Brain pathology (Zurich, Switzerland) · 2019Article
- Article
- Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma.Analytical cellular pathology (Amsterdam) · 2018Article
- Molecular Testing of Brain Tumor.Journal of pathology and translational medicine · 2017Review
- Intracranial Solitary Fibrous Tumor.Journal of the Belgian Society of Radiology · 2017Article
- Solitary fibrous tumour presenting with a single bone metastasis: report of six cases and literature review.Clinical sarcoma research · 2016Article
- Meningeal Hemangiopericytoma in 33-Year-Old Female; a Case Report.Iranian journal of pathology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe term solitary fibrous tumor (SFT) is preferred over meningeal hemangiopericytoma (HPC), because NAB2-STAT6 gene fusion has been observed in both intracranial and extracranial HPCs. HPCs are now considered cellular variants of SFTs.
methodsThis study analyzes 19 patients with STAT6-confirmed SFTs, who were followed for over 11 years in a single institution. Ten patients (10/19, 56.2%) had extracranial metastases (metastatic group), while the remainder (9/19) did not (non-metastatic group). These two groups were compared clinicopathologically.
resultsIn the metastatic group, the primary metastatic sites were the lungs (n = 6), bone (n = 4), and liver (n = 3). There was a mean lag time of 14.2 years between the diagnosis of the initial meningeal tumor to that of systemic metastasis. The median age at initial tumor onset was 37.1 years in the metastatic group and 52.5 in the non-metastatic group. The 10-year survival rates of the metastatic- and non-metastatic groups were 100% and 33%, respectively. The significant prognostic factors for poor outcomes on univariate analysis included advanced age (≥45 years) and large initial tumor size (≥5 cm). In contrast, the patients with higher tumor grade, high mitotic rate (≥5/10 high-power fields), high Ki-67 index (≥5%), and the presence of necrosis or CD34 positivity showed tendency of poor prognosis but these parameters were not statistically significant poor prognostic markers.
conclusionsAmong patients with SFTs, younger patients (<45 years) experienced longer survival times and paradoxically had more frequent extracranial metastases after long latent periods than did older patients. Therefore, young patients with SFTs require careful surveillance and follow-up for early detection of systemic metastases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.