Evidence map›Paper›PMID 26657167›Full record

ArticleBrain : a journal of neurology2016

Reply: Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion.

Patrick Yu-Wai-Man, Gavin Hudson, Thomas Klopstock, Patrick F Chinnery

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain : a journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Patrick Yu-Wai-Man1 Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK 2 Departments of Neurology and Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.
Gavin Hudson1 Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
Thomas Klopstock1 Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK 4 German Center for Neurodegenerative Diseases (DZNE), München, Germany 5 Munich Cluster for Systems Neurology (SyNergy), München, Germany.
Patrick F Chinnery1 Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK 6 Medical Research Council Mitochondrial Biology Unit, Cambridge, UK 7 Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, UK pfc25@medschl.cam.ac.uk.

Funding

Department of HealthMedical Research Council G0601943Medical Research Council G0701386Medical Research Council G1002570Medical Research Council MC_UP_1501/2Medical Research Council MR/K000608/1Wellcome Trust 096919Z/11/ZWellcome Trust 101876Wellcome Trust 101876/Z/13/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHumansOptic Atrophy, Autosomal DominantOptic Atrophy, Hereditary, Leber

Identifiers

PMID26657167
PMCPMC5839597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.