ArticleBrain : a journal of neurology2016
Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion.
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Article in Brain : a journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37citing papers in PubMed
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Who cites it
37 citing papers in PubMed.
- Predictors of Final Visual Outcome in Patients With Leber Hereditary Optic Neuropathy Treated With Lenadogene Nolparvovec Gene Therapy.Investigative ophthalmology & visual science · 2025Trial
- Advances in Primary Mitochondrial Diseases: Diagnosis, Natural History Studies and Clinical Trials.Genes · 2026Review
- Modifier variants in metabolic pathways are associated with an increased penetrance of Leber's Hereditary Optic Neuropathy.European journal of human genetics : EJHG · 2026Article
- Oxidative Stress and Inflammatory Biomarkers in Aqueous Humor and Blood of Patients with Leber's Hereditary Optic Neuropathy.Antioxidants (Basel, Switzerland) · 2025Article
- Evaluation of Visual and Optical Coherence Tomography Outcomes in Patients with Leber's Hereditary Optic Neuropathy Treated with Idebenone.Life (Basel, Switzerland) · 2025Article
- The crossroads of Leber hereditary optic neuropathy and autosomal dominant optic Atrophy: Clinical profiles of patients with coexisting pathogenic genetic variants.American journal of ophthalmology case reports · 2025Article
- The landscape of rare mitochondrial DNA variants in sudden cardiac death: A potential role for ATP synthase.Heliyon · 2025Article
- Serum neuronal, glial and mitochondrial markers in autosomal dominant optic atrophy and Leber hereditary optic neuropathy.Brain communications · 2025Article
- Late-onset Leber's hereditary optic neuropathy and antiandrogens for prostate cancer: is there a causative link?Frontiers in neurology · 2025Article
- Leber's Hereditary Optic Neuropathy.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- A Case of Late-Onset Leber's Hereditary Optic Neuropathy in Association with Heteroplasmic m.11778G>A/ND4 Mutation.Neuro-ophthalmology (Aeolus Press) · 2025Article
- Mitochondria in Retinal Ganglion Cells: Unraveling the Metabolic Nexus and Oxidative Stress.International journal of molecular sciences · 2024Review
- Evaluation of Mitochondrial Dysfunction and Idebenone Responsiveness in Fibroblasts from Leber's Hereditary Optic Neuropathy (LHON) Subjects.International journal of molecular sciences · 2023Article
- Low disease risk and penetrance in Leber hereditary optic neuropathy.American journal of human genetics · 2023Article
- Case report: Mutations inFrontiers in neurology · 2023Article
- Solutions to a Radical Problem: Overview of Current and Future Treatment Strategies in Leber's Hereditary Opic Neuropathy.International journal of molecular sciences · 2022Review
- Modeling Reactive Oxygen Species-Induced Axonal Loss in Leber Hereditary Optic Neuropathy.Biomolecules · 2022Article
- Article
- Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.Cell reports · 2022Article
- Endocrine Manifestations and New Developments in Mitochondrial Disease.Endocrine reviews · 2022Article
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Authors and funding
19 authors.
Valerio Carelli1 IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy 2 Neurology Unit, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy valerio.carelli@unibo.it alfredo.sadun@gmail.com.
Pio d'Adamo3 Medical Genetics, Department of Reproductive Sciences, Development and Public Health, University of Trieste, Trieste, Italy 4 IRCCS-Burlo Garofolo Children Hospital, Trieste, Italy.
Maria Lucia Valentino1 IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy 2 Neurology Unit, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Chiara La Morgia1 IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy 2 Neurology Unit, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Fred N Ross-Cisneros5 Doheny Eye Institute, Los Angeles, CA, USA.
Leonardo Caporali1 IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy.
Alessandra Maresca1 IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy 2 Neurology Unit, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Paola Loguercio Polosa6 Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.
Piero Barboni7 IRCCS Istituto Scientifico San Raffaele, Milan, Italy.
Annamaria De Negri8 Azienda San Camillo-Forlanini, Rome, Italy.
Federico Sadun9 Ospedale San Giovanni Evangelista, Tivoli, Italy.
Rustum Karanjia10 Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Solange R Salomao11 Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP) and IPEPO (Instituto da Visão), Sao Paulo, Brazil.
Adriana Berezovsky11 Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP) and IPEPO (Instituto da Visão), Sao Paulo, Brazil.
Filipe Chicani11 Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP) and IPEPO (Instituto da Visão), Sao Paulo, Brazil.
Milton Moraes12 Instituto de Olhos de Colatina, Colatina, Brazil.
Milton Moraes Filho12 Instituto de Olhos de Colatina, Colatina, Brazil.
Rubens Belfort11 Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP) and IPEPO (Instituto da Visão), Sao Paulo, Brazil.
Alfredo A Sadun5 Doheny Eye Institute, Los Angeles, CA, USA 10 Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, California, USA valerio.carelli@unibo.it alfredo.sadun@gmail.com.
Funding
VISION RESEARCHP30EY003040 · NEI · DOHENY EYE INSTITUTE · PI SUN, DEMING · 1985 to 2013
$7.0MMedical Research Council G0701386NEI NIH HHS EY03040
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsHumansOptic Atrophy, Autosomal DominantOptic Atrophy, Hereditary, Leber
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Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.