Evidence map›Paper›PMID 26656863›Full record

ArticleJournal of the American Heart Association2015

Heart Retransplant Recipients Have Better Survival With Concurrent Kidney Transplant Than With Heart Retransplant Alone.

Jill Savla, Kimberly Y Lin, Madhura Pradhan, Rebecca L Ruebner, Rachel S Rogers, Somaly S Haskins, Anjali T Owens, Peter Abt, J William Gaynor, Robert E Shaddy and 1 more

Abstract read
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In one paragraph

Article in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Heart retransplant recipients with renal dysfunction benefit from simultaneous heart-kidney transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  5. Simultaneous Heart-Kidney Transplant-Does Hospital Experience With Heart Transplant or Kidney Transplant Have a Greater Impact on Patient Outcomes?Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  6. Article
  7. Review
  8. End-stage renal disease after pediatric heart transplantation: A 25-year national cohort study.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jill SavlaDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Kimberly Y LinDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Madhura PradhanDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Rebecca L RuebnerDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Rachel S RogersDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Somaly S HaskinsDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Anjali T OwensDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Peter AbtDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
J William GaynorDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Robert E ShaddyDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).
Joseph W RossanoDepartment of Pediatrics, The Cardiac Center, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (J.S., K.Y.L., M.P., R.L.R., R.S.R., S.S.H., A.T.O., P.A., W.G., R.E.S., J.W.R.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart retransplant (HRT) recipients represent a growing number of transplant patients. The impact of concurrent kidney transplants (KTs) in this population has not been well studied. We tested the hypothesis that recipients of HRT with concurrent KT (HRT-KT) would have worse survival than recipients of HRT alone. METHODS AND

resultsA retrospective analysis of the United Network of Organ Sharing database was performed for all patients undergoing HRT from 1987 to 2011. There were 1660 HRT patients, of which 116 (7%) received concurrent KT. Those who received HRT-KT had older age, longer wait-list time, worse kidney function, and more known diabetes. Survival among recipients of HRT-KT was significantly better than that of recipients of HRT alone (P=0.005). A subgroup of 323 HRT patients with severe kidney dysfunction (estimated glomerular filtration rate <30 mL/min per 1.73 m(2) or on dialysis) was studied in more detail, and 76 (24%) received concurrent KT. Those on dialysis at the time of HRT had better survival with versus without concurrent KT (P<0.0001). On multivariable analysis, concurrent KT was independently associated with better outcomes for all patients with HRT and for the subgroup of patients with severe kidney dysfunction.

conclusionsRecipients of HRT-KT have better survival than recipients of HRT alone. Further research is needed to determine which HRT patients may benefit the most from concurrent KT.

Indexed as

AdultAge FactorsFemaleGlomerular Filtration RateHeart TransplantationHumansKaplan-Meier EstimateKidney DiseasesKidney TransplantationMaleMiddle AgedReoperationRetrospective StudiesRisk FactorsSurvival AnalysisWaiting Listsheartkidneysurvivaltransplantation

Identifiers

PMID26656863
PMCPMC4845285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.