Evidence map›Paper›PMID 26656478›Full record

ArticleAmerican journal of epidemiology2016

The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium.

E Susan Amirian, Georgina N Armstrong, Renke Zhou, Ching C Lau, Elizabeth B Claus, Jill S Barnholtz-Sloan, Dora Il'yasova, Joellen Schildkraut, Francis Ali-Osman, Siegal Sadetzki and 23 more

Abstract read
In one paragraph

Article in American journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Aspirin, NSAIDs, and Glioma Risk: Original Data from the Glioma International Case-Control Study and a Meta-analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Pooled it
  4. Pooled it
  5. Article
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  10. Impact ofPharmacogenomics and personalized medicine · 2023
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  20. Cancer management and research · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

E Susan Amirian
Georgina N Armstrong
Renke Zhou
Ching C Lau
Elizabeth B Claus
Jill S Barnholtz-Sloan
Dora Il'yasova
Joellen Schildkraut
Francis Ali-Osman
Siegal Sadetzki
Christoffer Johansen
Richard S Houlston
Robert B Jenkins
Daniel Lachance
Sara H Olson
Jonine L Bernstein
Ryan T Merrell
Margaret R Wrensch
Faith G Davis
Rose Lai
Sanjay Shete
Christopher I Amos
Michael E Scheurer
Kenneth Aldape
Irina Alafuzoff
Thomas Brännström
Helle Broholm
Peter Collins
Caterina Giannini
Marc Rosenblum
Tarik Tihan
Beatrice S Melin
Melissa L Bondy

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2002 to 2026
$57.4M
GENETIC EPIDEMIOLOGY OF MALIGNANT GLIOMAR01CA052689 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WIENCKE, JOHN K., WRENSCH, MARGARET R. · 1991 to 2015
$20.5M
International Case Control Study of Malignant GliomaR01CA139020 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BONDY, MELISSA L. · 2010 to 2015
$16.0M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA015083NCI NIH HHS P30 CA016672NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA125123NCI NIH HHS P30CA125123NCI NIH HHS P50 CA097257NCI NIH HHS R01 CA052689NCI NIH HHS R01 CA139020NCI NIH HHS R01CA139020NCI NIH HHS R01CA52689PHS HHS P50097257
6 · The paper itself

Abstract

Decades of research have established only a few etiological factors for glioma, which is a rare and highly fatal brain cancer. Common methodological challenges among glioma studies include small sample sizes, heterogeneity of tumor subtypes, and retrospective exposure assessment. Here, we briefly describe the Glioma International Case-Control (GICC) Study (recruitment, 2010-2013), a study being conducted by the Genetic Epidemiology of Glioma International Consortium that integrates data from multiple data collection sites, uses a common protocol and questionnaire, and includes biospecimen collection. To our knowledge, the GICC Study is the largest glioma study to date that includes collection of blood samples, which will allow for genetic analysis and interrogation of gene-environment interactions.

Indexed as

International CooperationAdolescentAdultAgedAged, 80 and overCase-Control StudiesFemaleGene-Environment InteractionGenetic Predisposition to DiseaseGliomaHumansIncidenceMaleMiddle AgedMolecular EpidemiologyRetrospective Studiescancercase-control studiesglioblastomagliomamethodologystudy profile

Identifiers

PMID26656478
PMCPMC4706682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.