ReviewNature reviews. Nephrology2016
Long-term effects of paediatric kidney transplantation.
Review in Nature reviews. Nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 53 citations in OpenAlex.
- Perioperative severe hemorrhage in pediatric kidney transplantation: frequency, risk factors, and outcomes.Pediatric nephrology (Berlin, Germany) · 2026Article
- Aligning Words With What Matters: Evaluation of a Nationwide Sample of Pediatric Kidney Transplant Educational Materials.Pediatric transplantation · 2026Article
- Association Between Age at Kidney Transplantation and Risk of Early Graft Loss.Pediatric transplantation · 2026Article
- Outcomes of single kidney transplantation from small pediatric donors aged <5 years: comparative analysis between pediatric and adult recipients.Renal failure · 2025Article
- Drug Usage and Risk for Polypharmacy After Pediatric Solid Organ Transplantation-A National Register Study.Clinical transplantation · 2025Article
- Belatacept Conversion in Adolescent Kidney Transplant Recipients: A Solution for the Critical Challenge of Adherence?Kidney international reports · 2025Article
- Long-Term Clinical Outcomes of Paediatric Kidney Transplantation in Hong Kong-A Territory-Wide Study.Nephrology (Carlton, Vic.) · 2025Article
- Medication adherence and outcomes after paediatric kidney transplantation: results from a telemedicine-based, multimodal aftercare approach.Frontiers in nephrology · 2025Article
- Genetic testing in pediatric kidney transplant recipients to promote informed choice and improve individualized monitoring.Orphanet journal of rare diseases · 2024Article
- Kidney Transplant in Children: Strategic Timing During Summer School Breaks.Kidney medicine · 2024Article
- Holistic care and symptom management for pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2024Article
- Clinical questions and good practice statements of clinical practice guidelines for management of kidney injury during anticancer drug therapy 2022.Clinical and experimental nephrology · 2024Article
- Long-term outcome after combined or sequential liver and kidney transplantation in children with infantile and juvenile primary hyperoxaluria type 1.Frontiers in pediatrics · 2023Article
- Analysis of risk factors and establishment of a risk prediction model for post-transplant diabetes mellitus after kidney transplantation.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- Pharmaceutical services based on therapeutic care pathway for kidney transplantation from donors of infants and young children: a single-center experience.Translational pediatrics · 2022Article
- Long-term outcomes during 37 years of pediatric kidney transplantation: a cohort study comparing ethnic groups.Pediatric nephrology (Berlin, Germany) · 2021Article
- Overexpression of aquaporin 2 in renal tubular epithelial cells alleviates pyroptosis.Translational andrology and urology · 2021Article
- Cancer After Pediatric Kidney Transplantation: A Long-term Single-center Experience in Japan.Transplantation direct · 2021Article
- The current status of kidney transplantation in Nigerian children: still awaiting light at the end of the tunnel.Pediatric nephrology (Berlin, Germany) · 2021Article
- Longitudinal Follow-Up on Cardiopulmonary Exercise Capacity Related to Cardio-Metabolic Risk Factors in Children With Renal Transplants.Frontiers in sports and active living · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal transplantation in paediatric patients usually provides excellent short-term and medium-term results. Early diagnosis of chronic kidney disease and active therapy of end-stage renal disease before and after transplantation enables the majority of children to grow and develop normally. The adverse effects of immunosuppressive medication and reduced graft function might, however, hamper long-term outcomes in these patients and can lead to metabolic complications, cardiovascular disease, reduced bone health, and malignancies. The neurocognitive development and quality of life of paediatric transplant recipients largely depend on the primary diagnosis and on graft function. Poor adherence to immunosuppression is an important risk factor for graft loss in adolescents, and controlled transition to adult care is of utmost importance to ensure a continued normal life. In this Review, we discuss the outcomes and long-term effects of renal transplantation in paediatric recipients, including consequences on growth, development, bone, metabolic, and cardiovascular disorders. We discuss the key problems in the care of paediatric renal transplant recipients and the remaining challenges that should be the focus of future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.