ArticleThe American naturalist2015
The Role of Standing Variation in Geographic Convergent Adaptation.
Article in The American naturalist, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 74 citations in OpenAlex.
- Effect of population structure and stabilizing selection on quantitative genetic variation.Genetics · 2026Article
- Identifying the Degree of Gene Reuse During Repeated Adaptation.Molecular ecology · 2025Review
- Artificial selection for resistance to copper and off-target physiological and behavioral effects inbioRxiv : the preprint server for biology · 2025Article
- Genome-wide Parallelism Underlies Rapid Freshwater Adaptation Fueled by Standing Genetic Variation in a Wild Fish.Molecular biology and evolution · 2025Article
- Rapid Parallel Adaptation in Distinct Invasions of Ambrosia Artemisiifolia Is Driven by Large-Effect Structural Variants.Molecular biology and evolution · 2025Article
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- Variable parallelism in the genomic basis of age at maturity across spatial scales in Atlantic Salmon.Ecology and evolution · 2024Article
- Tissue-specific and cis-regulatory changes underlie parallel, adaptive gene expression evolution in house mice.PLoS genetics · 2024Article
- The genomic response to urbanization in the damselflyEvolutionary applications · 2023Article
- A critical review on applications of the Avrami equation beyond materials science.Journal of the Royal Society, Interface · 2023Review
- Maximum SNP FST Outperforms Full-Window Statistics for Detecting Soft Sweeps in Local Adaptation.Genome biology and evolution · 2022Article
- Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution.PLoS genetics · 2022Review
- Review
- Population Structure Limits Parallel Evolution in Sticklebacks.Molecular biology and evolution · 2021Article
- Article
- Genomic basis of parallel adaptation varies with divergence inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- De Novo Mutation and Rapid Protein (Co-)evolution during Meiotic Adaptation in Arabidopsis arenosa.Molecular biology and evolution · 2021Article
- Phylogeographic and demographic modeling analyses of the multiple origins of the rheophytic goldenrod Solidago yokusaiana Makino.Heredity · 2021Article
- Global adaptation complicates the interpretation of genome scans for local adaptation.Evolution letters · 2021Article
- Detection of hard and soft selective sweeps from Drosophila melanogaster population genomic data.PLoS genetics · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The extent to which populations experiencing shared selective pressures adapt through a shared genetic response is relevant to many questions in evolutionary biology. In this article, we explore how standing genetic variation contributes to convergent genetic responses in a geographically spread population. Geographically limited dispersal slows the spread of each selected allele, hence allowing other alleles to spread before any one comes to dominate the population. When selectively equivalent alleles meet, their progress is substantially slowed, dividing the species range into a random tessellation, which can be well understood by analogy to a Poisson process model of crystallization. In this framework, we derive the geographic scale over which an allele dominates and the proportion of adaptive alleles that arise from standing variation. Finally, we explore how negative pleiotropic effects of alleles can bias the subset of alleles that contribute to the species' adaptive response. We apply the results to the malaria-resistance glucose-6-phosphate dehydrogenase-deficiency alleles, where the large mutational target size makes it a likely candidate for adaptation from deleterious standing variation. Our results suggest that convergent adaptation may be common. Therefore, caution must be exercised when arguing that strongly geographically restricted alleles are the outcome of local adaptation. We close by discussing the implications of these results for ideas of species coherence and the nature of divergence between species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.