Evidence map›Paper›PMID 26656140›Full record

Trial reportJACC. Heart failure2016

Do Non-Clinical Factors Improve Prediction of Readmission Risk?: Results From the Tele-HF Study.

Harlan M Krumholz, Sarwat I Chaudhry, John A Spertus, Jennifer A Mattera, Beth Hodshon, Jeph Herrin

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in JACC. Heart failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00303212 (A Study of Telemonitoring to Improve Heart Failure Outcomes), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00303212 nacompletednot on this map

A Study of Telemonitoring to Improve Heart Failure Outcomes

TypeinterventionalSponsorYale UniversityRan2006 to 2010Enrolled1,660ConditionsCongestive Heart FailureArmsTelemonitoring
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Can prediction models for hospital readmission be improved by incorporating patient-reported outcome measures? A systematic review and narrative synthesis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  2. Pooled it
  3. Analysis of Machine Learning Techniques for Heart Failure Readmissions.Circulation. Cardiovascular quality and outcomes · 2016
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Harlan M KrumholzSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut; Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut; Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut; Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut. Electronic address: harlan.krumholz@yale.edu.
Sarwat I ChaudhrySection of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
John A SpertusMid America Heart Institute, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
Jennifer A MatteraCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut.
Beth HodshonSection of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Jeph HerrinSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut; Health Research and Educational Trust, Chicago, Illinois.

Funding

Telemonitoring to improve heart failure outcomesR01HL080228 · NHLBI · YALE UNIVERSITY · PI KRUMHOLZ, HARLAN MARC · 2005 to 2008
$6.9M
Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
NHLBI NIH HHS R01 HL080228NHLBI NIH HHS U01 HL105270NHLBI NIH HHS U01 HL105270-05
6 · The paper itself

Abstract

objectivesThis study sought to determine whether a model that included self-reported socioeconomic, health status, and psychosocial characteristics obtained from patients recently discharged from hospitalizations for heart failure substantially improved 30-day readmission risk prediction compared with a model that incorporated only clinical and demographic factors.

backgroundExisting readmission risk models have poor discrimination and it is unknown whether they would be markedly improved by the inclusion of patient-reported information.

methodsAs part of the Tele-HF (Telemonitoring to Improve Heart Failure Outcomes) trial, we conducted medical record abstraction and telephone interviews in a sample of 1,004 patients recently hospitalized for heart failure to obtain clinical, functional, and psychosocial information within 2 weeks of discharge. Candidate risk factors included 110 variables divided into 2 groups: demographic and clinical variables generally available from the medical record; and socioeconomic, health status, adherence, and psychosocial variables from patient interview.

resultsThe 30-day readmission rate was 17.1%. Using the 3-level risk score derived from the restricted medical record variables, patients with a score of 0 (no risk factors) had a readmission rate of 10.9% (95% confidence interval [CI]: 8.2% to 14.2%), and patients with a score of 2 (all risk factors) had a readmission rate of 32.1% (95% CI: 22.4% to 43.2%), a C-statistic of 0.62. Using the 5-level risk score derived from all variables, patients with a score of 0 (no risk factors) had a readmission rate of 9.6% (95% CI: 6.1% to 14.2%), and patients with a score of 4 (all risk factors) had a readmission rate of 55.0% (95% CI: 31.5% to 76.9%), a C-statistic of 0.65.

conclusionsSelf-reported socioeconomic, health status, adherence, and psychosocial variables are not dominant factors in predicting readmission risk for patients with heart failure. Patient-reported information improved model discrimination and extended the predicted ranges of readmission rates, but the model performance remained poor. (Telemonitoring to Improve Heart Failure Outcomes [Tele-HF]; NCT00303212).

Indexed as

AdultAgedFemaleHealth StatusHeart FailureHumansMaleMiddle AgedMonitoring, AmbulatoryPatient-Centered CarePatient ReadmissionRisk AssessmentRisk FactorsSelf ReportSocioeconomic FactorsTelemedicineheart failureprognosisreadmission

Identifiers

PMID26656140
PMCPMC5459404

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.