Observational studyAnnals of surgery2016
Can Sarcopenia Quantified by Ultrasound of the Rectus Femoris Muscle Predict Adverse Outcome of Surgical Intensive Care Unit Patients as well as Frailty? A Prospective, Observational Cohort Study.
Observational study in Annals of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 94 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Assessment of Muscle to Quantify Frailty.
Effects of Mobility Dose in Surgical Intensive Care Unit Patients on Adverse Discharge Disposition
Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients
Identifying Modifiable PAtient Centered Therapeutics Frailty: An Observational Cohort Study
Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women
Who cites it
94 citing papers in PubMed, 4 syntheses or guidelines pooled it, 201 citations in OpenAlex.
- Expert Consensus on Morphofunctional Assessment in Disease-Related Malnutrition. Grade Review and Delphi Study.Nutrients · 2023Pooled it
- Prevalence and mortality risk of low skeletal muscle mass in critically ill patients: an updated systematic review and meta-analysis.Frontiers in nutrition · 2023Pooled it
- The current use of ultrasound to measure skeletal muscle and its ability to predict clinical outcomes: a systematic review.Journal of cachexia, sarcopenia and muscle · 2022Pooled it
- The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis.Intensive care medicine · 2017Pooled it
- Low rectus femoris mass index is closely associated with diabetic peripheral neuropathy.Frontiers in endocrinology · 2023Trial
- Frailty is associated with prolonged hospitalization and inferior patient-reported outcomes after acute quadriceps tendon rupture: A multicenter cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Point-of-care quadriceps muscle ultrasound as a predictor of postoperative delirium in older adults: a prospective cohort study.European geriatric medicine · 2026Observational
- Muscle morphology changes over 1-year in patients with rheumatoid arthritis: a prospective cohort study using muscle ultrasound.Advances in rheumatology (London, England) · 2026Observational
- Point-of-Care Ultrasound-Based Assessment of Sarcopenia to Predict Revisits or Mortality in Older Adults at the Emergency Department: A Prospective Observational Study.Annals of geriatric medicine and research · 2026Observational
- Impact of pre-operative frailty on hospital length of stay in major abdominal oncological surgeries: A prospective, observational study.Indian journal of anaesthesia · 2026Article
- Article
- Rectus femoris ultrasound identifies sarcopenia and predicts poor outcomes in patients with acute decompensation of cirrhosis.JHEP reports : innovation in hepatology · 2025Article
- Frailty: An overlooked red flag in sports surgery.Journal of experimental orthopaedics · 2025Article
- Balancing Rehabilitation Dose in Acute Stroke Decision-Making and Global Assessment (The BRIDGE Study).Journal of clinical medicine · 2025Article
- Association between bioelectrical impedance analysis parameters and muscle-related measurements obtained using a non-diagnostic ultrasound-based technique.Journal of translational medicine · 2025Article
- Ultrasound-based assessment of muscle mass is associated with early recovery after kidney transplant: a prospective single-center study.BMC anesthesiology · 2025Article
- Prevalence of frailty and its effect on requirement of organ support and clinical outcomes in critically ill patients: a prospective observational single center study.BMC anesthesiology · 2025Observational
- Impact of the Clinical Frailty Score on Outcomes of Critically Ill Patients in a Tertiary Care ICU.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- A sarcopenia prediction model based on the calf maximum muscle circumference measured by ultrasound.BMC geriatrics · 2025Article
- A w-ACT model for sarcopenia among community-dwelling older adults based on National Basic Public Health Services: development and validation study.Frontiers in public health · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 3 countries.
Funding
Abstract
objectiveTo compare sarcopenia and frailty for outcome prediction in surgical intensive care unit (SICU) patients.
backgroundFrailty has been associated with adverse outcomes and describes a status of muscle weakness and decreased physiological reserve leading to increased vulnerability to stressors. However, frailty assessment depends on patient cooperation. Sarcopenia can be quantified by ultrasound and the predictive value of sarcopenia at SICU admission for adverse outcome has not been defined.
methodsWe conducted a prospective, observational study of SICU patients. Sarcopenia was diagnosed by ultrasound measurement of rectus femoris cross-sectional area. Frailty was diagnosed by the Frailty Index Questionnaire based on 50 variables. Relationship between variables and outcomes was assessed by multivariable regression analysis NCT02270502.
resultsSarcopenia and frailty were quantified in 102 patients and observed in 43.1% and 38.2%, respectively. Sarcopenia predicted adverse discharge disposition (discharge to nursing facility or in-hospital mortality, odds ratio 7.49; 95% confidence interval 1.47-38.24; P = 0.015) independent of important clinical covariates, as did frailty (odds ratio 8.01; 95% confidence interval 1.82-35.27; P = 0.006); predictive ability did not differ between sarcopenia and frailty prediction model, reflected by χ values of 21.74 versus 23.44, respectively, and a net reclassification improvement (NRI) of -0.02 (P = 0.87). Sarcopenia and frailty predicted hospital length of stay and the frailty model had a moderately better predictive accuracy for this outcome.
conclusionsBedside diagnosis of sarcopenia by ultrasound predicts adverse discharge disposition in SICU patients equally well as frailty. Sarcopenia assessed by ultrasound may be utilized as rapid beside modality for risk stratification of critically ill patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.