ReviewEuropean heart journal2016
Intracoronary imaging of coronary atherosclerosis: validation for diagnosis, prognosis and treatment.
Review in European heart journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of the PCSK9 Antibody AliroCuMab on Coronary Atherosclerosis in PatieNts With Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy And Optical Coherence Tomography Imaging Study
Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography in Patients With Premature Coronary Artery Disease: a Randomized Controlled Trial
Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Effect of ezetimibe-statin combination therapy vs. statin monotherapy on coronary atheroma phenotype and lumen stenosis in patients with coronary artery disease: a meta-analysis and trial sequential analysis.Frontiers in pharmacology · 2024Pooled it
- Automated Coronary Optical Coherence Tomography Feature Extraction with Application to Three-Dimensional Reconstruction.Tomography (Ann Arbor, Mich.) · 2022Pooled it
- Prediction of acute coronary syndrome within 3 years using radiomics signature of pericoronary adipose tissue based on coronary computed tomography angiography.European radiology · 2022Trial
- Comprehensive risk prediction of acute coronary syndrome by integrating coronary plaque morphology and hemodynamic characteristics.Quantitative imaging in medicine and surgery · 2026Article
- Explainable ML for ACS culprit plaques: a multidimensional CCTA model highlighting hemodynamic increment.The international journal of cardiovascular imaging · 2026Article
- Spontaneous Coronary Artery Dissection or Coronary Atherosclerosis: Diagnostic Challenges in an Unclear Case.JACC. Case reports · 2026Article
- Article
- Reporting trends and clinical impact of high-risk coronary plaques on cardiac CT angiography in CAD-RADS.European radiology · 2026Article
- Artificial Intelligence-Led Whole Coronary Artery OCT Analysis; Validation and Identification of Drug Efficacy and Higher-Risk Plaques.Circulation. Cardiovascular imaging · 2025Article
- Exploratory Study of the Effects of Irreversible Electroporation on Atherosclerotic Plaque in a Rabbit Model.Journal of cardiovascular translational research · 2025Article
- Efficacy and Safety of High-Frequency Optical Coherence Tomography (HF-OCT) for Coronary Imaging: A Multicenter Study.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Advantages of hybrid intravascular ultrasound-optical coherence tomography system in clinical practice.Frontiers in cardiovascular medicine · 2025Article
- Shining light on neurovascular disease.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Radiomics analysis of lesion-specific pericoronary adipose tissue to predict major adverse cardiovascular events in coronary artery disease.BMC medical imaging · 2024Article
- Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe.Science translational medicine · 2024Article
- Tissue characteristics of residual lesion in patients with acute coronary syndrome caused by plaque rupture versus plaque erosion: a single-center, retrospective, observational study.Nagoya journal of medical science · 2024Observational
- Hemodynamics of Saline Flushing in Endoscopic Imaging of Partially Occluded Coronary Arteries.Cardiovascular engineering and technology · 2024Article
- Review
- Value of CT‑derived fractional flow reserve in identifying patients with acute myocardial infarction based on coronary computed tomography angiography.Experimental and therapeutic medicine · 2023Article
- Magnetically assisted soft milli-tools for occluded lumen morphology detection.Science advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While coronary atherosclerosis is a leading cause of mortality, evaluation of coronary lesions was previously limited to either indirect angiographic assessment of the lumen silhouette or post mortem investigations. Intracoronary (IC) imaging modalities have been developed that allow for visualization and characterization of coronary atheroma in living patients. Used alone or in combination, these modalities have enhanced our understanding of pathobiological mechanisms of atherosclerosis, identified factors responsible for disease progression, and documented the ability of various medications to reverse the processes of plaque growth and destabilization. These methodologies have established a link between in vivo plaque characteristics and subsequent coronary events, thereby improving individual risk stratification, paving the way for risk-tailored systemic therapies and raising the option for pre-emptive interventions. Moreover, IC imaging is increasingly used during coronary interventions to support therapeutic decision-making in angiographically inconclusive disease, guide and optimize procedural results in selected lesion and patient subsets, and unravel mechanisms underlying stent failure. This review aims to summarize current evidence regarding the role of IC imaging for diagnosis and risk stratification of coronary atherosclerosis, and to describe its clinical role for guiding percutaneous coronary interventions. Future perspectives for in-depth plaque characterization using novel techniques and multimodality imaging approaches are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.