Evidence map›Paper›PMID 26655818›Full record

ArticleJournal of neurophysiology2016

Neuromodulatory influence of norepinephrine during developmental experience-dependent plasticity.

Randall M Golovin, Nicholas J Ward

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Randall M GolovinNeuroscience Graduate Program, Vanderbilt University, Nashville, Tennessee; Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee;
Nicholas J WardVanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee; Vanderbilt Vision Research Center, Vanderbilt University, Nashville, Tennessee; and Department of Psychology, Vanderbilt University, Nashville, Tennessee nicholas.j.ward@vanderbilt.edu.
Vanderbilt University · US

Funding

Cholinergic Mechanisms in Spatial AttentionR00MH093567 · NIMH · VANDERBILT UNIVERSITY · PI DISNEY, ANITA A · 2014 to 2016
$747k
NIMH NIH HHS R00 MH093567
6 · The paper itself

Abstract

Critical periods represent phases of development during which neuronal circuits and their responses can be readily shaped by stimuli. Experience-dependent plasticity that occurs within these critical periods can be influenced in many ways; however, Shepard et al. (J Neurosci 35: 2432-2437, 2015) recently singled out norepinephrine as an essential driver of this plasticity within the auditory cortex. This work provides novel insight into the mechanisms of critical period plasticity and challenges previous conceptions that a functional redundancy exists between noradrenergic and cholinergic influences on cortical plasticity.

Indexed as

Neuronal PlasticityNorepinephrineAcetylcholineAuditory CortexAcetylcholineNorepinephrineauditory cortexcritical periodneuromodulationnorepinephrineplasticity

Identifiers

PMID26655818
PMCPMC4961751
OpenAlexW2194116155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.