Evidence map›Paper›PMID 26655672›Full record

ArticleExperimental neurology2016

Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury.

Shaoping Hou, David M Carson, Di Wu, Michelle C Klaw, John D Houlé, Veronica J Tom

Open access · greenAbstract read
In one paragraph

Article in Experimental neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

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  14. Targeting the Dopaminergic System in Autoimmunity.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
  15. Review
  16. Article
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  18. Presynaptic Inhibition of Primary Nociceptive Signals to Dorsal Horn Lamina I Neurons by Dopamine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shaoping HouSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States. Electronic address: shaoping.hou@drexelmed.edu.
David M CarsonSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States.
Di WuSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States.
Michelle C KlawSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States.
John D HouléSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States.
Veronica J TomSpinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, United States. Electronic address: veronica.tom@drexelmed.edu.
Drexel University · US

Funding

Multipronged approach to promote functional axonal regeneration in the spinal cord after injuryR01NS085426 · NINDS · DREXEL UNIVERSITY · PI TOM, VERONICA JEAN · 2014 to 2024
$3.6M
NINDS NIH HHS R01 NS085426
6 · The paper itself

Abstract

Dopamine (DA) neurons in the mammalian central nervous system are thought to be restricted to the brain. DA-mediated regulation of urinary activity is considered to occur through an interaction between midbrain DA neurons and the pontine micturition center. Here we show that DA is produced in the rat spinal cord and modulates the bladder reflex. We observed numerous tyrosine hydroxylase (TH)

Indexed as

AnimalsAnimals, NewbornCholine O-AcetyltransferaseDisease Models, AnimalDopamineDopamine AgentsEnzyme-Linked Immunosorbent AssayFemaleGanglia, ParasympatheticGanglia, SympatheticGreen Fluorescent ProteinsHerpesvirus 1, SuidNeuronsOxidopamineRatsRats, Inbred F3442-hydroxy-4,4'-diamidinostilbene, methanesulfonate saltCholine O-AcetyltransferaseDopamineDopamine Agentsdopamine dithiocarbamateGreen Fluorescent ProteinsOxidopamineStilbamidinesThiocarbamatesTyrosine 3-MonooxygenaseBladderDopamineInjurySpinal cord

Identifiers

PMID26655672
PMCPMC4889553
OpenAlexW2184202588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.