Evidence map›Paper›PMID 26655430›Full record

Trial reportContemporary clinical trials2016

The feasibility and acceptability of a diet and exercise trial in overweight and obese black breast cancer survivors: The Stepping STONE study.

Vanessa B Sheppard, Jennifer Hicks, Kepher Makambi, Alejandra Hurtado-de-Mendoza, Wendy Demark-Wahnefried, Lucile Adams-Campbell

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 18 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 18 syntheses or guidelines pooled it.

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  4. Effect of therapeutic exercise on peak oxygen consumption in oncological population: a systematic review with meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  13. Body weight management in overweight and obese breast cancer survivors.The Cochrane database of systematic reviews · 2020
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  15. Dietary interventions for adult cancer survivors.The Cochrane database of systematic reviews · 2019
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  18. Weight Loss Randomized Intervention Trials in Female Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vanessa B SheppardBreast Cancer Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven St., NW Suite 4100, Washington, DC 20007, USA; Office of Minority Health & Health Disparities Research, Lombardi Comprehensive Cancer Center, Georgetown University, 1000 New Jersey Ave., SE, Washington, DC 20003, USA. Electronic address: vls3@georgetown.edu.
Jennifer HicksOffice of Minority Health & Health Disparities Research, Lombardi Comprehensive Cancer Center, Georgetown University, 1000 New Jersey Ave., SE, Washington, DC 20003, USA.
Kepher MakambiDepartment of Biostatistics, Georgetown University, 4000 Reservoir Rd., NW, Washington, DC 20057, USA.
Alejandra Hurtado-de-MendozaBreast Cancer Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven St., NW Suite 4100, Washington, DC 20007, USA.
Wendy Demark-WahnefriedUniversity of Alabama at Birmingham Comprehensive Cancer Center, 1824 6th Ave S, Birmingham, AL, 35233, USA.
Lucile Adams-CampbellOffice of Minority Health & Health Disparities Research, Lombardi Comprehensive Cancer Center, Georgetown University, 1000 New Jersey Ave., SE, Washington, DC 20003, USA.

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Subproject 2: Verifying Information and Communication Technology and Outcomes P60MD006920 · NIMHD · GEORGETOWN UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, KIDWELL, CHELSEA S · 2012 to 2016
$6.3M
PREDICTORS OF ADJUVANT ENDOCRINE THERAPY ADHERENCE IN WOMEN WITH BREAST CANCERR01CA154848 · NCI · GEORGETOWN UNIVERSITY · PI SHEPPARD, VANESSA B · 2011 to 2015
$2.5M
IMPROVING EXERCISE AND DIET IN AFRICAN AMERICAN BREAST CANCER SURVIVORSR21CA149996 · NCI · GEORGETOWN UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, SHEPPARD, VANESSA B · 2010 to 2011
$362k
NCI NIH HHS P30 CA051008NCI NIH HHS P30CA51008NCI NIH HHS R01 CA154848NCI NIH HHS R21 CA149996NCI NIH HHS R21CA149996NIMHD NIH HHS P60 MD006920
6 · The paper itself

Abstract

purposeBlack breast cancer survivors have high rates of obesity and low physical activity levels. Little is known about the acceptability and feasibility of interventions in this population.

objectiveA two-arm RCT was launched to assess the efficacy of a culturally targeted 12-week multimodal lifestyle intervention in overweight and obese black survivors.

methodsIntervention components included nutrition education, exercise groups, and survivor-led motivational interviewing phone sessions. The analytic sample included women who completed the trial (intervention n=10; control n=12). Anthropometric measures, physical activity, and VO2max were assessed at baseline and follow-up. Change scores (intervention vs. control) were assessed with Wilcoxon rank-sum tests. A process evaluation assessed intervention acceptability.

resultsOverall adherence was 70% and overall satisfaction was high (86%). Despite the 5% weight loss target, the intervention group lost 0.8% but BMI improved. Total physical activity levels increased in the intervention vs. control arm (+3501METmin/week vs. +965METmin/week, respectively). VO2max improved in the intervention group (+0.10±1.03kg/L/min). Intervention participants reduced energy intake (-207.3±31.5kcals) and showed improvements in fat intake (-15.5±3.8g), fiber (+3.2±1.2g) and % energy from fat (-4.8±3.1%). Survivors suggested providing diet/exercise information within a cancer context.

conclusionsGroup and individualized intervention strategies are acceptable to black survivors. Observed differences between self-report and objective outcomes may suggest reporting bias or changes in body composition. Increasing supervised intervention components and assessment of body composition will be important for future trials.

Indexed as

Black or African AmericanBreast NeoplasmsPatient Acceptance of Health CareSurvivorsAdultAnthropometryBody CompositionBody Mass IndexDiet TherapyEnergy IntakeExercise TherapyFeasibility StudiesFemaleHumansLife StyleMiddle AgedAfrican AmericanBlackBreast cancerPhysical activitySurvivors

Identifiers

PMID26655430
PMCPMC5091075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.