Evidence map›Paper›PMID 26655100›Full record

Trial reportJournal of neurologic physical therapy : JNPT2016

Highly Challenging Balance Program Reduces Fall Rate in Parkinson Disease.

David Sparrow, Tamara R DeAngelis, Kathryn Hendron, Cathi A Thomas, Marie Saint-Hilaire, Terry Ellis

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neurologic physical therapy : JNPT, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 5 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
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  4. Interventions for preventing falls in Parkinson's disease.The Cochrane database of systematic reviews · 2022
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  20. A scoping review of the nature of physiotherapists' role to avoid fall in people with Parkinsonism.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David SparrowVA Boston Healthcare System and Department of Medicine (D.S.), Boston University School of Medicine, Boston, Massachusetts; Center for Neurorehabilitation (T.R.D., K.H., T.E.), Department of Physical Therapy and Athletic Training, College of Health and Rehabilitation Sciences: Sargent, Boston University, Boston, Massachusetts; and Department of Neurology (C.A.T., M.S.H.), Boston University Medical Campus, Boston University, Boston, Massachusetts.
Tamara R DeAngelis
Kathryn Hendron
Cathi A Thomas
Marie Saint-Hilaire
Terry Ellis
VA Boston Healthcare System · USAmerican Parkinson Disease Association · USBoston University · US

Funding

TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
NIA NIH HHS 5P30AG031679NIA NIH HHS P30 AG031679
6 · The paper itself

Abstract

background and purposeThere is a paucity of effective treatment options to reduce falls in Parkinson disease (PD). Although a variety of rehabilitative approaches have been shown to improve balance, evidence of a reduction in falls has been mixed. Prior balance trials suggest that programs with highly challenging exercises had superior outcomes. We investigated the effects of a theory-driven, progressive, highly challenging group exercise program on fall rate, balance, and fear of falling.

methodsTwenty-three subjects with PD participated in this randomized cross-over trial. Subjects were randomly allocated to 3 months of active balance exercises or usual care followed by the reverse. During the active condition, subjects participated in a progressive, highly challenging group exercise program twice weekly for 90 minutes. Outcomes included a change in fall rate over the 3-month active period and differences in balance (Mini-Balance Evaluation Systems Test [Mini-BESTest]), and fear of falling (Falls Efficacy Scale-International [FES-I]) between active and usual care conditions.

resultsThe effect of time on falls was significant (regression coefficient = -0.015 per day, P < 0.001). The estimated rate ratio comparing incidence rates at time points 1 month apart was 0.632 (95% confidence interval, 0.524-0.763). Thus, there was an estimated 37% decline in fall rate per month (95% confidence interval, 24%-48%). Improvements were also observed on the Mini-BESTest (P = 0.037) and FES-I (P = 0.059). DISCUSSION AND

conclusionsThe results of this study show that a theory-based, highly challenging, and progressive exercise program was effective in reducing falls, improving balance, and reducing fear of falling in PD.Video abstract available for more insights from the authors (see Supplemental Digital Content 1, http://links.lww.com/JNPT/A120).

Indexed as

Accidental FallsAgedCross-Over StudiesExercise TherapyFearFemaleHumansMaleMiddle AgedOutcome Assessment, Health CareParkinson DiseasePostural BalanceTreatment Outcome

Identifiers

PMID26655100
PMCPMC4681297
OpenAlexW2273399358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.