ArticleCell cycle (Georgetown, Tex.)2015
A new role for PGRP-S (Tag7) in immune defense: lymphocyte migration is induced by a chemoattractant complex of Tag7 with Mts1.
Article in Cell cycle (Georgetown, Tex.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- A New Function of the S100-A4 Protein (Mts1): Mts1 Stimulates the Activation of Cytotoxic Lymphocytes via the TREM-1 Receptor.International journal of molecular sciences · 2026Article
- Pglyrp1-Cre marks distinct epithelial and immune lineages across mucosal sites.ImmunoHorizons · 2026Article
- Pglyrp1-Cre Marks Distinct Epithelial and Immune Lineages Across Mucosal Sites.bioRxiv : the preprint server for biology · 2025Article
- PGRP-S promotes hepatocellular carcinoma progression via MAPK/ERK pathway by interaction with TTC1.Scientific reports · 2025Article
- Obesity alters the mouse endometrial transcriptome in a cell context-dependent manner.Reproductive biology and endocrinology : RB&E · 2022Article
- Tag7-Mts1 Complex Activates Chemotaxis of Regulatory T Cells.Doklady. Biochemistry and biophysics · 2022Article
- Myeloid cell interferon responses correlate with clearance of SARS-CoV-2.Nature communications · 2022Article
- Myeloid cell interferon responses correlate with clearance of SARS-CoV-2.Research square · 2021Article
- A 8-mer Peptide of PGLYRP1/Tag7 Innate Immunity Protein Binds to TNFR1 Receptor and Inhibits TNFα-Induced Cytotoxic Effect and Inflammation.Frontiers in immunology · 2021Article
- Article
- Tracking the important role ofOncology letters · 2020Article
- Peptidoglycan Recognition Protein 2 Regulates Neutrophil Recruitment Into the Lungs AfterFrontiers in microbiology · 2019Article
- Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota.Frontiers in immunology · 2019Article
- Membrane heat shock protein 70: a theranostic target for cancer therapy.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Tag7 (PGLYRP1) Can Induce an Emergence of the CD3+CD4+CD25+CD127+ Cells with Antitumor Activity.Journal of immunology research · 2018Article
- Peptidoglycan Recognition Protein 3 Does Not Alter the Outcome of Pneumococcal Pneumonia in Mice.Frontiers in microbiology · 2018Article
- The role of S100A4 protein in anticancer cytotoxicity: its presence is required on the surface of CDCell cycle (Georgetown, Tex.) · 2018Article
- Lymphocytes incubated in the presence of IL-2 lose the capacity for chemotaxis but acquire antitumor activity.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2017Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PGRP-S (Tag7) is an innate immunity protein involved in the antimicrobial defense systems, both in insects and in mammals. We have previously shown that Tag7 specifically interacts with several proteins, including Hsp70 and the calcium binding protein S100A4 (Mts1), providing a number of novel cellular functions. Here we show that Tag7-Mts1 complex causes chemotactic migration of lymphocytes, with NK cells being a preferred target. Cells of either innate immunity (neutrophils and monocytes) or acquired immunity (CD4(+) and CD8(+) lymphocytes) can produce this complex, which confirms the close connection between components of the 2 branches of immune response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.