Evidence map›Paper›PMID 26654565›Full record

ArticleHealth and quality of life outcomes2015

Disease profile and health-related quality of life (HRQoL) using the EuroQol (EQ-5D + C) questionnaire for chronic metallic mercury vapor intoxication.

Nadine Steckling, Dietrich Plass, Stephan Bose-O'Reilly, Alfred Bogomir Kobal, Alexander Krämer, Claudia Hornberg

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nadine StecklingWHO Collaborating Centre for Occupational Health, Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Workgroup Paediatric Environmental Epidemiology, University Hospital Munich, Ziemssenstr. 1, D-80336, Munich, Germany. nadine.steckling@uni-bielefeld.de.
Dietrich PlassFederal Environment Agency, Section Exposure Assessment and Environmental Health Indicators, Corrensplatz 1, D-14195, Berlin, Germany. Dietrich.Plass@uba.de.
Stephan Bose-O'ReillyWHO Collaborating Centre for Occupational Health, Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Workgroup Paediatric Environmental Epidemiology, University Hospital Munich, Ziemssenstr. 1, D-80336, Munich, Germany. Stephan.BoeseOReilly@med.uni-muenchen.de.
Alfred Bogomir KobalDepartment of Occupational Medicine, Idrija Mercury Mine, Idrija, Slovenia. abkobal@amis.net.
Alexander KrämerSchool of Public Health, Department of Public Health Medicine, Bielefeld University, Universitätsstraße 25, D-33615, Bielefeld, Germany. alexander.kraemer@uni-bielefeld.de.
Claudia HornbergSchool of Public Health, Department of Environment & Health, Bielefeld University, Universitätsstraße, 25, D-33615, Bielefeld, Germany. claudia.hornberg@uni-bielefeld.de.
Bielefeld University · DEMünchen Klinik · DEGerman Environment Agency · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToxic mercury is still being used today for example by workers mining gold, resulting in diverse health symptoms in users and individuals in proximity. A considerable burden of disease (BoD) can be assumed, while previous analyses were limited by data scarcity. Besides limited epidemiological data, neither data about the health-related quality of life (HRQoL) nor about the disease severity (disability weight, DW) is available. The aim of the project was to develop disease profiles of chronic metallic mercury vapor intoxication (CMMVI) by including the HRQoL to improve the data basis for BoD analyses of gold miners exposed to mercury.

methodsDisease profiles comprising the disease label [a], differentiation into disease stages [b], description of the cause of exposure [c], a list of common symptoms [d], and an assessment of the HRQoL [e] were developed using expert elicitation and literature search. The HRQoL was assessed by experts using the five EuroQol dimensions accompanied by the cognition add-on questionnaire (EQ-5D + C).

resultsThe ten sources used for the analyses (interview transcript, presentation, and eight literature reviews) identified more than 250 terms describing 85 distinguishable health effects of CMMVI. The analysis revealed 29 common symptoms that were frequently mentioned. Moderate and severe CMMVI cases differ regarding their symptoms and/or symptom severity and HRQoL, resulting in the EQ-5D + C-3L codes 121222 and 233333, respectively.

conclusionsThe profiles should be used to facilitate the ascertainment of CMMVI cases, to compare the HRQoL with other diseases, to derive DWs for improving BoD estimates, and to foster discussions about how to reduce the associated burden.

Indexed as

AdultAir Pollutants, OccupationalCross-Sectional StudiesFemaleHumansMaleMercuryMiningOccupational ExposurePersons with DisabilitiesQuality of LifeSurveys and QuestionnairesAir Pollutants, OccupationalMercury

Identifiers

PMID26654565
PMCPMC4675011
OpenAlexW2194961848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.