Evidence map›Paper›PMID 26654246›Full record

ArticleACS nano2016

Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation.

Daniel Roxbury, Prakrit V Jena, Yosi Shamay, Christopher P Horoszko, Daniel A Heller

Abstract read
In one paragraph

Article in ACS nano, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. High-throughput SWCNT NIR-II screening enables cell andbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Differential near-infrared imaging of heterocysts using single-walled carbon nanotubes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  11. Article
  12. Biosensing with Fluorescent Carbon Nanotubes.Angewandte Chemie (International ed. in English) · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Optimization of ssDNA-SWCNT Ultracentrifugation via Efficacy Measurements.ECS journal of solid state science and technology : JSS · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel RoxburyMemorial Sloan Kettering Cancer Center , New York, New York 10065, United States.
Prakrit V JenaMemorial Sloan Kettering Cancer Center , New York, New York 10065, United States.
Yosi ShamayMemorial Sloan Kettering Cancer Center , New York, New York 10065, United States.
Christopher P HoroszkoMemorial Sloan Kettering Cancer Center , New York, New York 10065, United States.
Daniel A HellerMemorial Sloan Kettering Cancer Center , New York, New York 10065, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
CANCER PHARMACOLOGYT32CA062948 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORRAINE J GUDAS · 1994 to 2026
$12.1M
Transient Metabolite Detection for Single-Cell Metabolomics and DiagnosticsDP2HD075698 · NICHD · SLOAN-KETTERING INST CAN RESEARCH · PI HELLER, DANIEL ALAN · 2012 to 2012
$2.7M
Influences of nanomechanical forces on T cellsR01GM110482 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUTTE, MANISH J · 2014 to 2018
$1.6M
NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA062948NICHD NIH HHS DP2 HD075698NIGMS NIH HHS R01 GM110482
6 · The paper itself

Abstract

Cell adhesion is a protein-mediated process intrinsic to most living organisms. Dysfunction in cell adhesion processes is implicated in various diseases, including thrombosis and metastatic cancers. Using an approach to resolve spectral features from cell membrane-associated photoluminescent single-walled carbon nanotubes, we found that nanotube optical bandgaps respond to the electrostatic potential of the cell surface, which corresponds to cell adhesion properties. We studied the carbon nanotube emission energy response to solution ionic potentials, which suggests sensitivity to local charge accumulation. We conclude that nanotubes respond to cell surface electrostatic potentials that are mediated by membrane proteins, which vary significantly across cell types. These findings portend the optical measurement of surface electrostatic potentials for biophysical measurements and biomedical applications.

Indexed as

AnimalsCell AdhesionHumansJurkat CellsLuminescent MeasurementsMembrane ProteinsMiceMolecular ImagingNanotubes, CarbonNIH 3T3 CellsOrgan SpecificitySpectrophotometry, InfraredStatic ElectricitySurface PropertiesThermodynamicsTime-Lapse ImagingMembrane ProteinsNanotubes, Carbonfluorescencein vivo spectroscopylive cell measurementsnanobiotechnologynear-infrared sensorsoptical biophysics

Identifiers

PMID26654246
PMCPMC4975035

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.