Evidence map›Paper›PMID 26654212›Full record

Trial reportJournal of consulting and clinical psychology2016

Staying well during pregnancy and the postpartum: A pilot randomized trial of mindfulness-based cognitive therapy for the prevention of depressive relapse/recurrence.

Sona Dimidjian, Sherryl H Goodman, Jennifer N Felder, Robert Gallop, Amanda P Brown, Arne Beck

5 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 77 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03294148 nacompletednot on this mapstarted 2017, after this paper: background citation

Mind-body Treatments for Chronic Back Pain

TypeinterventionalSponsorUniversity of Colorado, BoulderRan2017 to 2019Enrolled151ConditionsChronic Pain, Back Pain Lower Back Chronic, Back Pain, LowArmsOpen-Label Placebo Treatment for Chronic Back Pain, Psychotherapy Treatment for Chronic Back Pain
NCT03623620 nacompletednot on this mapstarted 2019, after this paper: background citation

Preventing Depressive Relapse in Pregnant Women With Recurrent Depression

TypeinterventionalSponsorMassachusetts General HospitalRan2019 to 2022Enrolled500ConditionsDepression, Pregnancy Related, Antenatal DepressionArmsDigital Delivery of Mindfulness-Based Cognitive Therapy
NCT03809572 naterminatednot on this mapstarted 2019, after this paper: background citation

Mechanisms of Action of MBCT-PD: A Pilot Study

TypeinterventionalSponsorOregon Health and Science UniversityRan2019 to 2021Enrolled56ConditionsMaternal Psychological Distress, Postpartum Depression, Prenatal StressArmsMindfulness Based Cognitive Therapy
NCT03809598 nacompletednot on this mapstarted 2019, after this paper: background citation

A Targeted Approach to Examine the Influence of Maternal Psychological Stress on Newborn Brain Outcomes

TypeinterventionalSponsorOregon Health and Science UniversityRan2019 to 2022Enrolled140ConditionsMaternal Psychological Distress, Prenatal Stress, Infant Development, Functional NeuroimagingArmsMindfulness Based Cognitive Therapy
NCT05000879 nacompletednot on this mapstarted 2018, after this paper: background citation

A Randomized Controlled Trial of Mental Health Outcomes and Putative Targets of an Online Mindfulness Program for New and Expectant Mothers

TypeinterventionalSponsorUniversity of Colorado, BoulderRan2018 to 2019Enrolled60ConditionsDepression, Pregnancy Related, Antenatal Depression, Depression, PostpartumArmsMMB for Moms
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sona DimidjianDepartment of Psychology and Neuroscience, University of Colorado Boulder.
Sherryl H GoodmanDepartment of Psychology, Emory University.
Jennifer N FelderDepartment of Psychology and Neuroscience, University of Colorado Boulder.
Robert GallopDepartment of Mathematics, Applied Statistics Program, West Chester University.
Amanda P BrownDepartment of Psychology, Emory University.
Arne BeckKaiser Permanente Colorado-Institute for Health Research.

Funding

Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal DepressionR34MH083866 · NIMH · UNIVERSITY OF COLORADO · PI DIMIDJIAN, SONA · 2008 to 2010
$651k
NIMH NIH HHS R34 MH083866NIMH NIH HHS R34MH083866
6 · The paper itself

Abstract

objectiveClinical decision-making regarding the prevention of depression is complex for pregnant women with histories of depression and their health care providers. Pregnant women with histories of depression report preference for nonpharmacological care, but few evidence-based options exist. Mindfulness-based cognitive therapy has strong evidence in the prevention of depressive relapse/recurrence among general populations and indications of promise as adapted for perinatal depression (MBCT-PD). With a pilot randomized clinical trial, our aim was to evaluate treatment acceptability and efficacy of MBCT-PD relative to treatment as usual (TAU).

methodPregnant adult women with depression histories were recruited from obstetric clinics at 2 sites and randomized to MBCT-PD (N = 43) or TAU (N = 43). Treatment acceptability was measured by assessing completion of sessions, at-home practice, and satisfaction. Clinical outcomes were interview-based depression relapse/recurrence status and self-reported depressive symptoms through 6 months postpartum.

resultsConsistent with predictions, MBCT-PD for at-risk pregnant women was acceptable based on rates of completion of sessions and at-home practice assignments, and satisfaction with services was significantly higher for MBCT-PD than TAU. Moreover, at-risk women randomly assigned to MBCT-PD reported significantly improved depressive outcomes compared with participants receiving TAU, including significantly lower rates of depressive relapse/recurrence and lower depressive symptom severity during the course of the study.

conclusionsMBCT-PD is an acceptable and clinically beneficial program for pregnant women with histories of depression; teaching the skills and practices of mindfulness meditation and cognitive-behavioral therapy during pregnancy may help to reduce the risk of depression during an important transition in many women's lives.

Indexed as

AdultCognitive Behavioral TherapyDepressionDepression, PostpartumFemaleHumansMindfulnessPilot ProjectsPregnancyRecurrenceTreatment Outcome

Identifiers

PMID26654212
PMCPMC5718345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.