Evidence map›Paper›PMID 26653890›Full record

ArticleInfectious diseases of poverty2015

Seroprevalence of Toxoplasma gondii infection among patients with hand, foot and mouth disease in Henan, China: a hospital-based study.

Shuai Wang, Chunwei Lan, Luwen Zhang, Haizhu Zhang, Zhijun Yao, Dong Wang, Jingbo Ma, Jiarong Deng, Shiguo Liu

Abstract read
In one paragraph

Article in Infectious diseases of poverty, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Coinfection ofMicroorganisms · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Toxoplasma infection in individuals in central Italy: does a gender-linked risk exist?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuai WangDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. tongbaiws1003@163.com.
Chunwei LanDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. 120190273@qq.com.
Luwen ZhangDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. hertales@126.com.
Haizhu ZhangDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. zhanghaizhu@xxmu.edu.cn.
Zhijun YaoDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. 79231931@qq.com.
Dong WangDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. 041089@xxmu.edu.cn.
Jingbo MaDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. majingbo1223@163.com.
Jiarong DengDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. 986497408@qq.com.
Shiguo LiuDepartment of Human Parasitology, Xinxiang Medical University, Xinxiang, Henan, 453003, PR China. lsg1963@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of infection with Toxoplasma gondii (T. gondii) in humans has been increasing in China due to the growing number of cats in the country. Hand, foot and mouth disease (HFMD) is a serious public health issue in China and still one of the leading causes of child mortality. However, little is known about the epidemiology of T. gondii infection among HFMD patients.

methodsA case-control study of 281 HFMD patients from the First People's Hospital of Pingdingshan in Pingdingshan city, Henan province, central China, and 222 controls from Pingdingshan city was conducted. Anti-T. gondii antibodies were serologically detected using the enzyme-linked immunosorbent assay.

resultsWe found that the overall anti-T. gondii immunoglobulin G (IgG) antibody prevalence among HFMD patients was 12.46 %, which was significantly higher than that in clinically healthy children (1.80 %). The highest T. gondii seroprevalence was detected in critical cases (22.58 %), followed by severe cases (11.50 %), and the lowest was detected in mild cases (8.33 %).

conclusionThe present study is the first survey of T. gondii seroprevalence among HFMD patients in China; 12.46 % were defined as seropositive. It is imperative that improved integrated measures are taken to prevent and control T. gondii infection among HFMD patients.

Indexed as

CoinfectionAnimalsAntibodies, ProtozoanCase-Control StudiesCatsChildChild, PreschoolChinaEnzyme-Linked Immunosorbent AssayFemaleHand, Foot and Mouth DiseaseHospitalizationHumansImmunoglobulin GInfantMaleAntibodies, ProtozoanImmunoglobulin G

Identifiers

PMID26653890
PMCPMC4675030

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.