ArticleGenome biology2015
A genome-wide survey of DNA methylation in hexaploid wheat.
Article in Genome biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
52 citing papers in PubMed.
- Nonadditive gene expression and reduced homoeolog expression bias in an intraspecific hexaploid wheat hybrid.BMC plant biology · 2026Article
- Harnessing genomics approaches for heat stress resilience in wheat: from discovery to deployment.Journal of experimental botany · 2026Review
- DNA methylation around transcription start sites is not globally associated with transcription in the grain of natural and synthetic hexaploid wheat.BMC plant biology · 2026Article
- Testing the potential of zebularine to induce heritable changes in crop growth and development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- The Genetics and Breeding of Heat Stress Tolerance in Wheat: Advances and Prospects.Plants (Basel, Switzerland) · 2025Review
- Decrypting molecular mechanism of heat stress tolerance in rice to tackle climate change challenges through recent approaches.Frontiers in plant science · 2025Review
- DNA methylation in wheat: current understanding and future potential for enhancing biotic and abiotic stress tolerance.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Transgenerational epigenetic inheritance during plant evolution and breeding.Trends in plant science · 2024Review
- Characteristics ofHorticulture research · 2023Article
- Conferring of Drought and Heat Stress Tolerance in Wheat (Nanomaterials (Basel, Switzerland) · 2023Article
- Triticeae crop genome biology: an endless frontier.Frontiers in plant science · 2023Review
- Transcriptional gene silencing in bread wheat (Triticum aestivum L.) and its application to regulate male fertility for hybrid seed production.Plant biotechnology journal · 2022Article
- Circadian regulation of the transcriptome in a complex polyploid crop.PLoS biology · 2022Article
- Integration of DNA Methylation and Transcriptome Data Improves Complex Trait Prediction inPlants (Basel, Switzerland) · 2022Article
- N6-Methyladenosine dynamic changes and differential methylation in wheat grain development.Planta · 2022Article
- Flavonoid Biosynthesis Genes inBiomolecules · 2022Article
- BS-Seq reveals major role of differential CHH methylation during leaf rust resistance in wheat (Triticum aestivum L.).Molecular genetics and genomics : MGG · 2022Article
- Enhancer transcription detected in the nascent transcriptomic landscape of bread wheat.Genome biology · 2022Article
- Impacts, Tolerance, Adaptation, and Mitigation of Heat Stress on Wheat under Changing Climates.International journal of molecular sciences · 2022Review
- Physiological and molecular insights on wheat responses to heat stress.Plant cell reports · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundDNA methylation is an important mechanism of epigenetic gene expression control that can be passed between generations. Here, we use sodium bisulfite treatment and targeted gene enrichment to study genome-wide methylation across the three sub-genomes of allohexaploid wheat.
resultsWhile the majority of methylation is conserved across all three genomes we demonstrate that differential methylation exists between the sub-genomes in approximately equal proportions. We correlate sub-genome-specific promoter methylation with decreased expression levels and show that altered growing temperature has a small effect on methylation state, identifying a small but functionally relevant set of methylated genes. Finally, we demonstrate long-term methylation maintenance using a comparison between the D sub-genome of hexaploid wheat and its progenitor Aegilops tauschii.
conclusionsWe show that tri-genome methylation is highly conserved with the diploid wheat progenitor while sub-genome-specific methylation shows more variation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.