Evidence map›Paper›PMID 26653247›Full record

ArticleBMC infectious diseases2015

HIV treatment and care among Italian inmates: a one-month point survey.

R Monarca, G Madeddu, R Ranieri, S Carbonara, G Leo, M Sardo, F Choroma, S Casari, D Marri, A A Muredda and 3 more

Abstract readMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. HIV seroprevalence in five key populations in Europe: a systematic literature review, 2009 to 2019.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Pooled it
  2. Pooled it
  3. Hepatitis B and C prevalence and incidence in key population groups with multiple risk factors in the EU/EEA: a systematic review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

R MonarcaInfectious Diseases Unit, Belcolle Hospital, Viterbo, Italy. roberto.monarca@gmail.com.
G MadedduInfectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 35b, 07100, Sassari, Italy. giordano@uniss.it.
R RanieriInfectious Diseases Unit, A.O. San Paolo, Milan, Italy. roberto.ranieri@ao-sanpaolo.it.
S CarbonaraInstitute of Infectious Diseases, University of Bari, Bari, Italy. s_carbonara@yahoo.it.
G LeoInfectious Diseases Unit, Amedeo di Savoia Hospital, Torino, Italy. dhc@libero.it.
M SardoCotugno Hospital, Infectious Diseases Unit, Naples, Italy. massimosardo@libero.it.
F ChoromaInfectious Diseases Unit, AUSL, Parma, Italy. fchoroma@ausl.pr.it.
S CasariInstitute of Infectious Diseases, University of Brescia, Brescia, Italy. s.casari@infettivibrescia.it.
D MarriInfectious Diseases Unit, A.O. Santa Maria alle Scotte, Siena, Italy. daniele.marri@libero.it.
A A MureddaInfectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 35b, 07100, Sassari, Italy. albertomuredda@hotmail.it.
F A NavaPenitentiary Medicine, Padova, Italy. felicealfonso.nava@sanita.padova.it.
S BabudieriInfectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 35b, 07100, Sassari, Italy. babuder@uniss.it.
SIMSPe–SIMIT Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV infection, with an estimated prevalence be between 2 and 50 times those of the general adult population is a major health challenge for prison authorities worldwide. Since no nationwide surveillance system is present in Italy, data on HIV prevalence and treatment in prisons are limited to only a few and small observational studies. We aimed to estimate HIV prevalence and obtain an overview on diagnostic and therapeutic activities concerning HIV infection in the Italian penitentiary system.

methodsWe piloted a multi-centre cross-sectional study investigating the prevalence of HIV infection and assessing HIV-related medical activities in Italian correctional institutions.

resultsA total of 15,675 prisoners from 25 institutions, accounting for approximately one-fourth of the prison inmates in Italy, were included in the study, of whom, 97.7 % were males, 37.1 % foreigners and 27 % had a history of intravenous drug addiction. HIV-tests were available in 42.3 % of the total population, with a known HIV Infection proportion of 5.1 %. In the month prior to the study, 604 of the 1,764 subjects who entered prison were tested for HIV, with a HIV-positive prevalence of 3.3 %. Among the 338 HIV-positive prisoners, 81.4 % were under antiretroviral treatment and 73.5 % showed undetectable HIV-RNA. In 23/338 (6.8 %) a coinfection with HBV and in 189/338 (55.9 %) with HCV was also present. Among the 67 (19.8 %) inmates with HIV who did not receive HIV treatment, 13 (19.5 %) had T-CD4+ count <350 cells/mm(3) and 9 (69.2 %) of these had refused the treatment. The majority of the inmates with HIV-infection were on a PI-based (62.5 %) or on NNRTIs-based (24.4 %) regimen. Only a minority of patients received once daily regimens (17.2 %).

conclusionsAlthough clinical and therapeutic management of HIV infection remains difficult in Italian prisons, diagnostics, treatment and care were offered to the majority of HIV-infected inmates. Specific programs should be directed towards the prison population and strict cooperation between prison and health institutions is needed to increase HIV treatment.

Indexed as

AdultAgedAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIVHIV InfectionsHumansItalyMaleMass ScreeningMedication AdherenceMiddle AgedPrevalencePrisonersAnti-HIV AgentsRNA, Viral

Identifiers

PMID26653247
PMCPMC4676105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.