ArticleParasites & vectors2015
The characterization and manipulation of the bacterial microbiome of the Rocky Mountain wood tick, Dermacentor andersoni.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Genome sequencing and multi-stage, blood-feeding, and tissue-specific transcriptome atlas of the Rocky Mountain wood tick provide a critical resource for this vector.Insect biochemistry and molecular biology · 2026Article
- Decoupling Abundance from Centrality: Sexual Dimorphism and Geographical Structuring in thePathogens (Basel, Switzerland) · 2026Article
- Beyond Dominant Symbionts: Low-Abundance Taxa Govern Microbial Network Topology in Sympatric Ticks.Microbial ecology · 2026Article
- Hidden caveats in tick dissection: engorgement level and complex tracheal network architecture compromise internal organ integrity.Journal of insect science (Online) · 2026Article
- Genome sequencing and multi-stage, blood-feeding, and tissue-specific transcriptome atlas of the Rocky Mountain wood tick provide a critical resource for this vector.bioRxiv : the preprint server for biology · 2026Article
- A systematic review of the microbiome ofVeterinary world · 2025Review
- Exploring the microbiomes of camel ticks to infer vector competence: insights from tissue-level symbiont-pathogen relationships.Scientific reports · 2025Article
- Composition of the Midgut Microbiota Structure ofAnimals : an open access journal from MDPI · 2024Article
- Diversity of midgut microbiota in ticks collected from white-tailed deer (Odocoileus virginianus) from northern Mexico.Parasites, hosts and diseases · 2024Article
- Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine.Scientific reports · 2023Article
- The dynamics of the microbiome in Ixodidae are shaped by tick ontogeny and pathogens in Sarawak, Malaysian Borneo.Microbial genomics · 2023Article
- Article
- Characterization and manipulation of the bacterial community in the midgut of Ixodes ricinus.Parasites & vectors · 2022Article
- Changes in theFrontiers in microbiology · 2022Article
- Recently EvolvedFrontiers in cellular and infection microbiology · 2022Article
- The bacterial biome of ticks and their wildlife hosts at the urban-wildland interface.Microbial genomics · 2021Article
- Microbiomes of Blood-Feeding Arthropods: Genes Coding for Essential Nutrients and Relation to Vector Fitness and Pathogenic Infections. A Review.Microorganisms · 2021Review
- Discovery and Surveillance of Tick-Borne Pathogens.Journal of medical entomology · 2021Article
- An integrated overview of the bacterial flora composition of Hyalomma anatolicum, the main vector of CCHF.PLoS neglected tropical diseases · 2021Article
- The genus Anaplasma: drawing back the curtain on tick-pathogen interactions.Pathogens and disease · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundIn North America, ticks are the most economically impactful vectors of human and animal pathogens. The Rocky Mountain wood tick, Dermacentor andersoni (Acari: Ixodidae), transmits Rickettsia rickettsii and Anaplasma marginale to humans and cattle, respectively. In recent years, studies have shown that symbiotic organisms are involved in a number of biochemical and physiological functions. Characterizing the bacterial microbiome of D. andersoni is a pivotal step towards understanding symbiont-host interactions.
findingsIn this study, we have shown by high-throughput sequence analysis that the composition of endosymbionts in the midgut and salivary glands in adult ticks is dynamic over three generations. Four Proteobacteria genera, Rickettsia, Francisella, Arsenophonus, and Acinetobacter, were identified as predominant symbionts in these two tissues. Exposure to therapeutic doses of the broad-spectrum antibiotic, oxytetracycline, affected both proportions of predominant genera and significantly reduced reproductive fitness. Additionally, Acinetobacter, a free-living ubiquitous microbe, invaded the bacterial microbiome at different proportions based on antibiotic treatment status suggesting that microbiome composition may have a role in susceptibility to environmental contaminants.
conclusionsThis study characterized the bacterial microbiome in D. andersoni and determined the generational variability within this tick. Furthermore, this study confirmed that microbiome manipulation is associated with tick fitness and may be a potential method for biocontrol.
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