Evidence map›Paper›PMID 26652029›Full record

ArticleLGBT health2016

A Dyadic Exercise Intervention to Reduce Psychological Distress Among Lesbian, Gay, and Heterosexual Cancer Survivors.

Charles Kamen, Charles Heckler, Michelle C Janelsins, Luke J Peppone, James M McMahon, Gary R Morrow, Deborah Bowen, Karen Mustian

Registry-linked trialAbstract read
In one paragraph

Article in LGBT health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03649737 (Pilot Study of a Progressive Exercise Program Among Lung Cancer Patient-Partner Dyads), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03649737 nacompletednot on this mapstarted 2018, after this paper: background citation

Pilot Study of a Progressive Exercise Program Among Lung Cancer Patient-Partner Dyads

TypeinterventionalSponsorOHSU Knight Cancer InstituteRan2018 to 2019Enrolled46ConditionsLung Cancer, Depression, Physical Activity, Quality of LifeArmsExercise Intervention, Survey Administration, Quality-of-Life Assessment
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
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  8. The effects of high-dose calcitriol and individualized exercise on bone metabolism in breast cancer survivors on hormonal therapy: a phase II feasibility trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Trial
  9. Identity among adolescent and young adult cancer survivors: an exploratory qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  10. Patient-reported quality-of-life outcomes in immune checkpoint inhibitor therapy: addressing gaps, capturing patient experience, and advancing the field.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  11. Article
  12. Review
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  14. Sexual and Gender Minority Invisibility in Cancer Studies: A Call for Effective Recruitment Methods to Address Cancer Disparities.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charles Kamen1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.
Charles Heckler1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.
Michelle C Janelsins1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.
Luke J Peppone1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.
James M McMahon2 School of Nursing, University of Rochester Medical Center , Rochester, New York.
Gary R Morrow1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.
Deborah Bowen3 School of Public Health, University of Washington , Seattle, Washington.
Karen Mustian1 Department of Surgery, University of Rochester Medical Center , Rochester, New York.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
UNIVERSITY OF ROCHESTER--CCOP RESEARCH BASEU10CA037420 · NCI · UNIVERSITY OF ROCHESTER · PI MORROW, GARY R · 1985 to 2014
$21.1M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
The University of Rochester Clinical and Translational Science InstituteKL2TR000095 · NCATS · UNIVERSITY OF ROCHESTER · PI BENNETT, NANCY M, KIEBURTZ, KARL D. · 2012 to 2015
$1.7M
Exercise Intervention for Lesbian, Gay, Bisexual, and Transgender Cancer SurvivorsK07CA190529 · NCI · UNIVERSITY OF ROCHESTER · PI KAMEN, CHARLES STEWART · 2015 to 2019
$830k
Interventions Targeting Inflammation for Chemotherapy-Related Cognitive ProblemsK07CA168886 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C · 2013 to 2017
$724k
Management of Cancer-Treatment-Induced Bone LossK07CA168911 · NCI · UNIVERSITY OF ROCHESTER · PI PEPPONE, LUKE JOSEPH · 2013 to 2017
$724k
NCI NIH HHS K07 CA168886NCI NIH HHS K07 CA168911NCI NIH HHS K07 CA190529NCI NIH HHS R25 CA102618NCI NIH HHS U10 CA037420NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

purposeStudies have found disparities in psychological distress between lesbian and gay cancer survivors and their heterosexual counterparts. Exercise and partner support are shown to reduce distress. However, exercise interventions haven't been delivered to lesbian and gay survivors with support by caregivers included.

methodsIn this pilot randomized controlled trial (RCT), ten lesbian and gay and twelve heterosexual survivors and their caregivers were randomized as dyads to: Arm 1, a survivor-only, 6-week, home-based, aerobic and resistance training program (EXCAP

resultsTwenty of the twenty-two recruited survivors were retained post-intervention. At baseline, lesbian and gay survivors reported significantly higher depressive symptoms (P = .03) and fewer average steps walked (P = .01) than heterosexual survivors. Post-intervention, these disparities were reduced and we detected no significant differences between lesbian/gay and heterosexual survivors. Participation in dyadic exercise resulted in a significantly greater reduction in depressive symptoms than participation in survivor-only exercise for all survivors (P = .03). No statistically significant differences emerged when looking across arm (survivor-only vs. dyadic) by subgroup (lesbian/gay vs. heterosexual).

conclusionExercise may be efficacious in ameliorating disparities in psychological distress among lesbian and gay cancer survivors, and dyadic exercise may be efficacious for survivors of diverse sexual orientations. Larger trials are needed to replicate these findings.

Indexed as

cancercaregiversexercisehealth disparitiesoncologysexual orientation

Identifiers

PMID26652029
PMCPMC4770846

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.